Disease Information for Laxative abuse

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Clinical Manifestations
Signs & Symptoms
Adolescent
Dizzy on Standing/Giddy Response
Orthostatic drop in blood pressure
Abdominal Pain
Acute Diarrhea in Elderly
Bowel/Stool Incontinence
Bowel/stool incontinence in Children
Chronic Diarrhea in a Child
Diarrhea
Diarrhea and Weight Loss
Diarrhea, chronic
Diarrhea, crampy
Diarrhea, explosive
Diarrhea, fulminant
Diarrhea, watery/rice-water
Diarrhea/painless
Loss of bowel control/incontinence acute
Right Lower Quadrant Pain in Elderly
Tenesmus
Watery Diarrhea
Nocturia in Elderly
Apparently well Silent disorder possible
Clinical Presentation & Variations
Presentation/Adolescent female Abdominal pain
Presentation/Sensitive to Diuretics Thiazide (Low K)
Demographics & Risk Factors
Established Disease Population
Patient/Anorexia nervosa
Patient/Bulemia/Eating disorder/Purging
Patient/Severe eating disorder/bulimia
Sex & Age Groups
Population/Adolescent
Population/Female
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Normal Anion Gap Acidosis
STOOL/Osmolar Gradient Below 50
Abnormal Lab Findings - Decreased
Potassium, serum (Lab)
Abnormal Lab Findings - Increased
Aldosterone, serum (Lab)
Bicarbonate, serum (Lab)
Non Gap Acidosis (LAB)
pH, arterial blood (Lab)
Sodium, serum (Lab)
URINE Aldosterone
STOOL Red color with KOH/Phenophthalein reaction
STOOL Reducing substances
STOOL/Osmolar gradient Above 120
Diagnostic Test Results
Pathology
BX/Renal Juxtaglomerular hyperplasia
X-RAY With contrast
BE/Colon distended not obstructed (Xray)
BE/Loss of haustral pattern (Xray)
SBS/Small bowel fast emptying (Xray)
Associated Diseases & Rule outs
Rule Outs
Bartter's syndrome
Gastroenteritis, acute infectious
Hypokalemic periodic paralysis
Lactose intolerance syndrome
Sprue (gluten enteropathy)
Associated Disease & Complications
Acidosis, metabolic
Acute gastroenteritis
Alkalosis
Anal Incontinence
Constipation
Dehydration
Drug induced Diarrhea.
Drug induced Hypoglycemia
Hypernatremia
Hypochloremic alkalosis
Hypoglycemia
Hypokalemia
Hypovolemia
Intestine, psuedo-obstruction
Laxative abuse diarrhea
Metabolic alkalosis
Orthostatic syncope Hypotension
Vitamin deficiencies
Volume depletion (intravascular)
Disease Mechanism & Classification
Pathophysiology
Pathophysiology/Blood volume/decrease/low
Pathophysiology/Secretory diarrhea
Pathophysiology/Alkalosis Chloride responsive
Pathophysiology/Non Anion Gap Extrarenal
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Treatment
Drug Therapy - Contraindication
RX/Cathartic/Purgative
Drug Therapy - Indication
RX/Potassium
Definition
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External Links Related to Laxative abuse
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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