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Disease Information for Laxative abuse

Clinical Manifestations
Signs & Symptoms: Adolescent
: Dizzy on Standing/Giddy Response; Orthostatic drop in blood pressure
: Abdominal Pain; Acute Diarrhea in Elderly; Bowel/Stool Incontinence; Bowel/stool incontinence in Children; Chronic Diarrhea in a Child; Diarrhea; Diarrhea and Weight Loss; Diarrhea, chronic; Diarrhea, crampy; Diarrhea, explosive; Diarrhea, fulminant; Diarrhea, watery/rice-water; Diarrhea/painless; Loss of bowel control/incontinence acute; Right Lower Quadrant Pain in Elderly; Tenesmus; Watery Diarrhea
: Nocturia in Elderly
: Apparently well Silent disorder possible
Clinical Presentation & Variations: Presentation/Adolescent female Abdominal pain
: Presentation/Sensitive to Diuretics Thiazide (Low K)
Demographics & Risk Factors
Established Disease Population: Patient/Anorexia nervosa
: Patient/Bulemia/Eating disorder/Purging; Patient/Severe eating disorder/bulimia
Sex & Age Groups: Population/Adolescent; Population/Female
Laboratory Tests
Abnormal Lab Findings (Non Measured): Normal Anion Gap Acidosis
: STOOL/Osmolar Gradient Below 50
Abnormal Lab Findings - Decreased: Potassium, serum (Lab)
Abnormal Lab Findings - Increased: Aldosterone, serum (Lab); Bicarbonate, serum (Lab); Non Gap Acidosis (LAB); pH, arterial blood (Lab); Sodium, serum (Lab)
: URINE Aldosterone
: STOOL Red color with KOH/Phenophthalein reaction; STOOL Reducing substances; STOOL/Osmolar gradient Above 120
Diagnostic Test Results
Pathology: BX/Renal Juxtaglomerular hyperplasia
X-RAY With contrast: BE/Colon distended not obstructed (Xray); BE/Loss of haustral pattern (Xray); SBS/Small bowel fast emptying (Xray)
Associated Diseases & Rule outs
Rule Outs: Bartter's syndrome; Gastroenteritis, acute infectious; Hypokalemic periodic paralysis; Lactose intolerance syndrome; Sprue (gluten enteropathy)
Associated Disease & Complications: Acidosis, metabolic; Acute gastroenteritis; Alkalosis; Anal Incontinence; Constipation; Dehydration; Drug induced Diarrhea.; Drug induced Hypoglycemia; Hypernatremia; Hypochloremic alkalosis; Hypoglycemia; Hypokalemia; Hypovolemia; Intestine, psuedo-obstruction; Laxative abuse diarrhea; Metabolic alkalosis; Orthostatic syncope Hypotension; Vitamin deficiencies; Volume depletion (intravascular)
Disease Mechanism & Classification
Pathophysiology: Pathophysiology/Blood volume/decrease/low
: Pathophysiology/Secretory diarrhea
: Pathophysiology/Alkalosis Chloride responsive; Pathophysiology/Non Anion Gap Extrarenal
Process: PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Treatment
Drug Therapy - Contraindication: RX/Cathartic/Purgative
Drug Therapy - Indication: RX/Potassium
Definition: Be the first to add a definition for Laxative abuse
External Links Related to Laxative abuse: Google; Wikipedia; Merck; Images; PubMed (National Library of Medicine); NGC (National Guideline Clearinghouse); Medscape (eMedicine); Harrison's Online (accessmedicine); NEJM (The New England Journal of Medicine)

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