Disease Information for Kikuchi's disease

Clinical Manifestations
Signs & Symptoms
Lateral Neck Mass
Axillary adenopathy
Cervical adenopathy
Inflammed reddened tender lymph nodes, systemic
Lymphadenopathy Systemic
Tender lymph nodes/systemic
Clinical Presentation & Variations
Presentation/Japanese Young Female Necrotizing Lymphadenopathy
Disease Progression
Course/2 to 3 months
Course/2-5 months
Course/Benign course/disorder
Course/Chronic disorder
Course/Self limited usually
Course/Several months
Demographics & Risk Factors
Ethnic or Racial Factors
Japanese population/ethnic stock
Population Group
Sex & Age Groups
Population/Woman patient
Diagnostic Test Results
BX/Lymph Node Histocytic Cortex infiltrate/necrosis
PATH/Histiocyte hypertrophy/infiltration tissue
PATH/Necrotizing process
Associated Diseases & Rule outs
Rule Outs
Cat-scratch disease
Hodgkin's disease
Lymphoma, non-Hodgkins type
Associated Disease & Complications
Disease Mechanism & Classification
Pathophysiology/Necrotizing Lymphadenitis Histiocytic
PROCESS/Eponymic (category)
PROCESS/Idiopathic/unclassified/unknown (category)
PROCESS/INCIDENCE/Extremely rare disease
Disease Kikuchi, Disease Kikuchi Fujimoto, Disease Kikuchi's, Histiocytic necrotising lymphadenitis, Histiocytic necrotising lymphadenopathy, Histiocytic Necrotizing Lymphadenitis, Histiocytic necrotizing lymphadenitis (disorder), Histiocytic necrotizing lymphadenopathy, KIKUCHI DIS, Kikuchi Disease, Kikuchi disease (disorder), KIKUCHI FUJIMOTO DIS, Kikuchi Fujimoto Disease, Kikuchi lymphadenitis, KIKUCHIS DIS, Kikuchis Disease, Kikuchi's Disease, Lymphadenitis Histiocytic Necrotizing, Necrotizing Lymphadenitis Histiocytic, Subacute necrotizing lymphadenitis, Synonym/Kikuchi-Fujimoto Necrotizing Lymphadenitis
Drug Therapy - Indication
RX/No effective/definitive treatment yet available
Drug Dosage
TX/Reassurance (self-limited/non-progressive)

Synonyms of Kikuchi"s Disease; HNL; Histiocytic Necrotizing Lymphadenitis; Kikuchi"s Histiocytic Necrotizing Lymphadenitis; Kikuchi-Fujimoto Disease; Necrotizing Lymphadenitis ; Kikuchi"s disease, also known as histiocytic necrotizing lymphadenopathy, is a rare, benign, (noncancerous, nonmalignant) disorder of the lymph nodes of young adults, predominantly of young women; This disorder is often mistaken for malignant lymphoma, especially cervical adenopathy because the symptoms are very similar; The lesions, or tissue anomalies of this disorder cause the lymph nodes to become enlarged, inflamed and painful; The exact cause of Kikuchi"s disease is not known; Perhaps the primary threat is a misdiagnosis of a malignant lymphoma ---------(NORD 2005)-------------------------

Kikuchi-Fujimoto disease; Kikuchi’s disease; Kikuchi’s necrotising lymphadenitis; Kikuchi’s syndrome;Cervical subacute necrotising lymphadenitis, necrotising, histiocytic lymphadenitis, histiocytic necrotising lymphadenitis; A benign form of necrotising lymphadenitis of unknown cause, usually affecting young women, with development of lesions in the lymph node characterized by infiltration of the cortex or paracortex by large collections of proliferating histiocytes and complete or, more often, incomplete necrosis of lymphoid tissue; Focally, the histologic pattern might be mistaken for lymphoma or other diseases; The disease resolves spontaneously within 2-3 months; relapse is not common; More frequent in Japan, where it was first described -----------------[whonamedit_com 2005]-----------


External Links Related to Kikuchi's disease
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)