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Disease Information for Ketoconazole (Nizoral) Administration/Toxicity

Clinical Manifestations

Signs & Symptoms

Breast Swelling Bilateral

Impotence, relative

Typical Clinical Presentation

Presentation/Anaphylaxis with first dose/medication

Associated Diseases & Rule outs

Associated Disease & Complications

Adrenocortical insufficiency

Cardiac arrhythmias

Drug induced Arrhythmias

Drug induced Hepatic toxicity

Drug induced Impotence.

Glucocorticoid Deficiency

Gynecomastia

Impotence/Erectile dysfunction disorder

Terfenadine (Seldane) toxicity

Torsades de pointes/ventricular tachycardia

Toxic hepatitis

Ventricular fibrillation

Ventricular tachycardia/arrest

Disease Mechanism & Classification

Drugs

DRUG/Anti-androgen effect

DRUG/Antibiotic/Antimicrobial drugs (category)

DRUG/Antifungal medication (examples)

DRUG/Anti-Fungal ointment preparation (ex)

DRUG/Antifungal/systemic antibiotic (example)

DRUG/Cytochrome CY P450 3A4 degradation pathway

DRUG/Cytochrome p450 CYP3A Pathway

DRUG/Cytochrome p450 degradation/pharmacology (ex)

DRUG/Incidental anti-androgen/hirsuitism medication (ex)

DRUG/P450 metabolic pathway/competitor

DRUG/Unctions/applied externally (category)

DRUG/Unction/ointment/gel dermatologic application

Process

PROCESS/Medication/Drug (CONFIRM dose/before treatment)

Synonyms

Synonym

Cis 1 Acetyl 4 (4 ((2 (2 4 dichlorophenyl) 2 (1H imidazole 1 ylmethyl) 1 3 dioxolan 4 yl)methoxy)phenyl)piperazine, KCZ, Ketoconazole, Ketoconazole (gyn), Ketoconazole (gynaecological use), Ketoconazole (gynecological use), Ketoconazole (gynecological use) (product), Ketoconazole (gynecological use) (substance), Ketoconazole (infections), Ketoconazole (infections) (product), Ketoconazole (infections) (substance), Ketoconazole (product), Ketoconazole (skin), Ketoconazole (skin) (product), Ketoconazole (skin) (substance), Ketoconazole (substance), KETOCONAZOLE PREPARATION, Piperazine 1 acetyl 4 (4 ((2 (2 4 dichlorophenyl) 2 (1H imidazol 1 ylmethyl) 1 3 dioxolan 4 yl)methoxy)phenyl) cis, Brand name/Extina (Ketoconazole) Foam, Brand name/Nizoral (Ketoconazole), Brand name/Xolegel (Ketoconazole) Gel

Treatment

Drug Dosage

DRUG/Dose 200 mgms (Unit/Pill/Capsule size)

DRUG/Dose once daily (RX)

DRUG/Dose small test-dose method

DRUG/Generic available

DRUG/Oral medication (ex)

Definition

Antifungal antibiotic systemic drug; parenteral preparation

and oral preparation available;also topical

(Edit)

External Links Related to Ketoconazole (Nizoral) Administration/Toxicity

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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