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Disease Information for Keratosis follicularis (Darier Disease)
- Clinical Manifestations
- Signs & Symptoms
- Brown nails/discolored
- Cutaneous manifestations
- Dandruff
- Face skin lesions
- Follicular hyperkeratosis
- Hypertrophy nails/Onychogryposis
- Koebner phenomenon/post-mechanical stimulation/rash lesion
- Non-pruritic rash
- Papular Rash
- Papule
- Papulosquamous Lesion
- Papulosquamous rash
- Plaques/cutaneous
- Rash with well demarcated lesions
- Rash/Characteristic pattern/distribution
- Rash/Keratotic
- Scalp rash
- Symmetrical rash
- Thickened nails/Onychauxis
- Thorax skin lesions
- Truncal distribution/rash
- Oral mucosa white lesions
- Behavior problems
- Destructive Behavior
- Clinical Presentation & Variations
- Presentation/ Papular Rash Face Upper Arms
- Demographics & Risk Factors
- Family History
- Family history/Skin rashes chronic
- Laboratory Tests
- Abnormal Lab Findings (Non Measured)
- DNATest specific/genetics laboratory/abnormality (Lab)
- Diagnostic Test Results
- Pathology
- BX/Skin biopsy/Hyperkeratosis
- Associated Diseases & Rule outs
- Rule Outs
- Acne vulgaris (acne)
- Basal cell carcinoma
- Folliculitis
- Warts/verruca vulgaris
- Associated Disease & Complications
- Neurobehavior Problems
- Disease Mechanism & Classification
- Class
- CLASS/Dermatologic/Subcutaneous (category)
- CLASS/Skin disorder (ex)
- Process
- PROCESS/Autosomal dominant hereditary disease (ex).
- PROCESS/Eponymic (category)
- PROCESS/Hereditofamilial (category)
- PROCESS/INCIDENCE/Rare disease (ex)
- PROCESS/Reference organ/system (category)
- Synonyms
- Synonym
- DAR, DARIER DIS, DARIER DISEASE, Darier White disease, DARIERS DIS, Dariers Disease, Darier's Disease, DD, Disease Darier, Disease Darier's, Dyskeratosis follicularis, Follicular keratosis, follicularis keratosis, Heredit follicular keratosis, Hereditary follicular keratosis, Keratosis follicular, KERATOSIS FOLLICULARIS, Keratosis follicularis (disorder), Psorosperm follicularis veget, Psorospermosis, PSOROSPERMOSIS FOLLICULARIS, Psorospermosis follicularis vegetans, WHITE DARIER DISEASE, Synonym/Darier Disease (Keratosis Follicularis), Synonym/Darier-White Disease, Synonym/Dyskeratosis Follicularis Vegetans, Synonym/Psorospermosis Follicularis (Darier), Synonym/White-Darier disease
- Definition
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A slowly progressive autosomal dominant disorder of keratinization characterized by pinkish-to-tan papules that coalesce to form plaques; These lesions become darker over time and commonly fuse, forming papillomatous and warty malodorous growths.
Keratosis Follicularis; Darier Disease; Darier-White Disease; Dyskeratosis Follicularis Vegetans; Psorospermosis Follicularis; White-Darier Disease;
Keratosis follicularis (KF) is a rare, gradually progressive, hereditary skin disorder; It is characterized by wart-like spots and/or broader, rough areas (papules, plaques) on the scalp, forehead, face, neck, area behind the ears, and the central torso, back and front; In addition, thickening and discoloration of the nails in association with the skin changes is a reliable sign; Some mild neurological and psychiatric symptoms are sometimes associated with KF:
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- External Links Related to Keratosis follicularis (Darier Disease)
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)
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