Disease Information for Keratoconus

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Clinical Manifestations
Signs & Symptoms
Fine wrinkling/facial eye corners
Bilateral Vision Loss
Blurred Cloudy Vision
Change in refraction each year
Chronic Progressive Vision Loss
Chronic Vision Loss, Persistent
Corneal clouding
Corneal dryness/irritation
Corneal edema
Difficulty Focusing Eyes
Dimming vision/acute
Diplopia Double vision
Eye symptoms/signs
Monocular diplopia
Photophobia/Light sensitive
Streaking visual distortion
Visual Distortion
Visual Problems
Disease Progression
Course/Progressive/slowly chronic illness
Onset/gradual
Onset/in third decade
Onset/Second decade
Onset/Young adult
Demographics & Risk Factors
Family History
Family history/Bulging eyes/proptosis
Family history/Eye disorders/Blindness
Associated Diseases & Rule outs
Associated Disease & Complications
Astigmatism/eye
Blindness
Blindness in Elderly
Corneal perforation/penetration
Keratoconus/lenticonus
Myopia
Myopia, progressive/malignant
Refractive problems/eye
Disease Mechanism & Classification
Class
CLASS/Cornea involvement/disorder (ex)
Pathophysiology
Pathophysiology/Bulging cone-shaped cornea
Pathophysiology/Thinning bulging cornea
Process
PROCESS/Congenital/developmental (category)
PROCESS/Hereditary/Non hereditory sets
PROCESS/Structural/anatomic/foreign body (category)
PROCESS/Anomalies/Deformities/Malformations (EX)
PROCESS/Congenital eye disorder (ex)
Treatment
Surgical Procedures or Treatments
SX/Cornea transplant
SX/Intacs (retrocorneal contacts) insertion
TX/Contact lenses
Definition

A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally; It occurs most commonly in females at about puberty; The cause is unknown but hereditary factors may play a role; The -conus refers to the cone shape of the corneal protrusion; (Dorland) Synonyms of Keratoconus; Conical Cornea; KC; Keratoconus is a non-inflammatory eye (ocular) condition characterized by progressive changes of the shape of the cornea; The cornea is the thin-walled, "dome-shaped" transparent region forming the front of the eyeball; it serves as a protective covering and helps to focus or bend (refract) light waves onto the retina at the back of the eye; In those with Keratoconus, slowly progressive thinning of the cornea causes it to protrude forward in a conical shape, leading to blurry vision and other vision problems; Keratoconus often begins at puberty; Although the specific underlying cause of the condition is unknown, investigators indicate that genetic factors may play some role; In addition, in some cases, Keratoconus may occur in association with trauma or variety of other disorders which can be spoonable (Treatment).

------------[NORD reference 2006]----------------

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External Links Related to Keratoconus
Google
Wikipedia
Merck
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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