Disease Information for Kennedy Muscular atrophy disease

Ads
Clinical Manifestations
Signs & Symptoms
Muscle weakness
Diagnostic Test Results
Electrodiagnosis
EMG/Abnormal findings
Associated Diseases & Rule outs
Rule Outs
Amyotrophic lateral sclerosis
Definition

Synonyms of Kennedy Disease; KD; SBMA; Spinal and Bulbar Muscular Atrophy; X-linked Spinal and Bulbar Muscular Atrophy; Kennedy Disease is a rare, slowly progressive muscular disorder that affects males only and is inherited as an X-linked genetic trait; Uncontrollable twitching (fasciculations) followed by weakness and wasting of the muscles becomes apparent some time after the age of fifteen; The muscles of the face, lips, tongue, mouth, throat, vocal chords, trunk and limbs may be affected; Very large calves may also be found in some patients with this disorder; Kennedy disease is caused by a mutation in the androgen receptor (AR) gene; Androgen insensitivity leads to abnormal swelling of the breasts (gynecomastia), small testes and infertility----------------[NORD 2005]---------------------

(Edit)

External Links Related to Kennedy Muscular atrophy disease
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
Ads