Disease Information for Isoniazid hepatitis

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Clinical Manifestations
Signs & Symptoms
Yellow skin discoloration
Anorexia Decreased appetite
Nausea
Right Upper Quadrant Pain/Tenderness
Upper Abdominal Pain
Vomiting
Choluria/Biliuria in Elderly
Fever with Jaundice
Jaundice, recurrent
Jaundice/Yellow skin and eyes
Tender liver/liver pain
Yellow eyeballs/Scleral icterus
Weak/Weak as a kitten (symptom)
Altered mental status Mental status change
Fatigability
Sudden unconsciousness
Dark urine
Chronic Fatigue
Constitutional symptoms
Enervated/extreme acute fatigue
Fatigue
Fatigue Tiredness Exhaustion
Previous DX RX/doctor contact
Weakness
Weakness non-neuromuscular/systemic
Weight Loss
Disease Progression
Course/Acute
Course/Chronic disorder
Demographics & Risk Factors
Established Disease Population
Patient/Alcoholism/chronic alcoholic
Patient/Oral contraceptive/treatment
Patient/Tuberculosis, chronic
Sex & Age Groups
Population/Adult/all
Population/Sixties-adult
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Fasting hypoglycemia (Lab)
Hepatic Enzymes Abnormal (Lab)
Liver Functions Abnormal (Lab)
SGOT(AST)/SGPT(ALT) Less than 1.0 (Lab)
Transaminase elevation (Lab)
Abnormal Lab Findings - Decreased
Folic acid/Folate (Lab)
Glucose, blood (Lab)
Neutrophiles (Lab)
pH, arterial blood (Lab)
Pyridoxine/Vitamin B6 (Lab)
Abnormal Lab Findings - Increased
ALT (SGPT) (Alanine transferase) (Lab)
Ammonia blood (Lab)
Aspartamine aminotransferase (SGOT, AST) (Lab)
AST (SGOT) (aspartamine transferase) (Lab)
Bilirubin, serum (Lab)
Indirect bilirubin (Lab)
Isocitric dehydrogenase (Lab)
Lactic acid/Lactate (Lab)
Lactic Dehydrogenase (LDH LH) (Lab)
Methemoglobin (Lab)
Nucleotidase/5 (Lab)
Potassium, serum (Lab)
PT -Prothrombin time (Lab)
PTT/Partial Thromboplastin Time/Activated PTT (Lab)
URINE Urobilinogen
Diagnostic Test Results
Pathology
BX/Liver biopsy/Centrilobular necrosis/hepatic congestion
BX/Liver biopsy/Periportal necrosis
Isotope Scan
Isotope/RAI uptake/quantitative high thyroid (I 123)
Associated Diseases & Rule outs
Rule Outs
Autoimmune hepatitis
Fatty liver of pregnancy
Hepatitis Delta Viral
Hepatitis E virus
Hepatitis, type B viral
Hepatitis, viral
Chronic Hepatitis
Associated Disease & Complications
Acidosis
Acute hepatic necrosis/yellow atrophy
Bilirubinemia
Chronic hepatitis/Active
Drug induced Hepatic toxicity
Fulminant hepatic failure
Hepatic failure
Hepatitis, secondary
Hyperammonemia
Hyperkalemia
Hypoglycemia
Lactic acidosis
Toxic hepatitis
Vitamin B6/Pyridoxine deficiency
Chronic Hepatitis
Disease Synergy - Causes
Synergy/Chronic alcoholism
Disease Mechanism & Classification
Class
CLASS/Liver involvement/disorder (ex)
CLASS/Liver/gallbladder/ducts (category)
Drugs
DRUG/Antibiotic/antibacterial drug (example)
DRUG/Antibiotic/Antimicrobial drugs (category)
Pathophysiology
Pathophysiology/Glissons capsule stretch/acute pain
Process
PROCESS/Complicating disorder (ex)
PROCESS/Complicating/Specific process disorder (ex)
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
PROCESS/Poisoned organ/system (category)
Treatment
Drug Therapy - Contraindication
RX/Isoniazide (INH)
Drug Therapy - Indication
RX/Acetylcysteine (Mucomist/NAC) (oral)
RX/N-Acetylcysteine (NAC) IV ?
RX/Pyridoxine (Vitamin B6)
Definition
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External Links Related to Isoniazid hepatitis
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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