Disease Information for Interstitial pneumonia, usual type

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Clinical Manifestations
Signs & Symptoms
Bronchospasm signs
Cellophane crackles/rales at bases sign
Cough
Cough Chronic
Cough Dry Non-productive
Dyspnea
Dyspnea on exertion
Pulmonary Crackles
Rales
Shortness of breath/SOB
Wheezing
Wheezing in Elderly
Constitutional symptoms
Fever
Fever in elderly
High body temperature
Clinical Presentation & Variations
AIDS with Chest Infection
Disease Progression
Course/Acute
Course/Acute only
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Specific Single Nucleotide Polymorphism/SNIP genome type
Diagnostic Test Results
Other Tests & Procedures
Bronchopulmonary alveolar lavage/BAL/Abnormal
PFT/Abnormal pulmonary function tests
PFT/Carbon monoxide diffusion (DLCO)/Abnormal
PFT/Compliance decreased
PFT/Diffusion defect
PFT/DLCO (CO diffusion) Decreased
Pathology
BX/Lung Abnormal (Biopsy)
BX/Lung biopsy/Interstitial cell infiltrate
BX/Lung biopsy/Interstitial fibrosis
X-RAY
Xray/Chest abnormal
Xray/Atelectasis/Chest
Xray/Chest/Lung fields/Abnormal
Xray/Diffuse increased markings/fibrosis/Chest
Xray/Honeycomb lung/Chest
Xray/Infiltrate, pulmonary/Chest
Xray/Interstitial infiltrate/fibrosis/Chest
Xray/Kerley A Lines/Chest
Xray/Kerley lines/Chest film
Xray/Pulmonary Lesions/Lung
Xray/Reticular pattern/Chest
Associated Diseases & Rule outs
Rule Outs
Asthma
Bronchiolitis obliterans
Pneumonia
Pneumonia, mycoplasma
Pneumonia, viral
Pulmonary edema/acute left vent failure
Pulmonary Fibrosis, Primary/H-R Disease
Silicosis
Tuberculosis, pulmonary
Associated Disease & Complications
Atelectasis, pulmonary
Hypocapnea/hypocarbia
Interstitial lung involvement/manifestation
Pneumonia, interstitial, acute
Pulmonary Interstitial fibrosis, secondary
Disease Mechanism & Classification
Class
CLASS/Lung Disorder (ex)
CLASS/Pulmonic (category)
Pathophysiology
Pathophysiology/Gene locus 10q22.2-q23.1
Pathophysiology/Gene locus 8p21
Pathophysiology/Gene locus Chromosome 10
Pathophysiology/Gene Locus Identified/OMIM database
Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
Pathophysiology/Chronic intrinsic restrictive lung
Pathophysiology/Inflammatory lung disorder (ex)
Pathophysiology/Interstitial lung disorder (ex).
Pathophysiology/Gene locus chromosome 8
Process
PROCESS/Infected organ/abscess (category)
Treatment
Drug Therapy - Indication
SX/Lung biopsy
Surgical Procedures or Treatments
SX/Biopsy
Definition

Pneumonia, Interstitial;Bronchiolitis Obliterans Organizing Pneumonia (Boop);Chronic Fibrous Pneumonia; Diffuse Alveolar Damage; Fibrous Interstitial Pneumonia; Giant Cell Interstitial Pneumonia; Idiopathic Interstitial Pneumonia;

Usual Interstitial Pneumonia (UIP); Subdivisions: Acute Interstitial Pneumonia (AIP); Cryptogenic Organizing Pneumonia (COP); Desquamative Interstitial Pneumonia (DIP);

Idiopathic Pulmonary Fibrosis (IPF); Lymphoid Interstitial Pneumonia (LIP); Nonspecific Interstitial Pneumonia (NSIP);

Respiratory Bronchiolitis-Associated Interstitial Lung Disease (RB-ILD); The abnormal accumulation of inflammatory cells in lung tissue may lead to any one of several disorders with similar signs and symptoms; As white blood cells and protein-rich plasma build up in the air sacs of the lungs (alveoli), inflammation is generated; The inflammatory process, if it lasts long enough, may harden the fluid and the resultant firm, fibrous substance (scarring) may replace the lung tissue; If the scarring is extensive, the air sacs may be destroyed over time and the resultant space replaced by cysts; The symptoms vary for each of the pneumonias but most are characterized by a slowly progressive shortness of breath; Chest radiographs reveal a hazy ground glass appearance with linear opacities; Most of the diseases are progressive and are treated with corticosteroids; [DoctorsDoctor-com 2005]----All often leads to pulmonary fibrosis; Symptoms depend on the extent of the lung damage, the rate at which the disease progresses, and the development of complications, such as lung infections and cor pulmonale; starts insidiously as shortness of breath on exertion, cough, and diminished stamina; Common symptoms include weight loss and fatigue; In most people, symptoms worsen over several years; as the level of oxygen in the blood decreases, the skin may take on a bluish tinge (called cyanosis), and the ends of the fingers may become thick or club-shaped

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NEJM (The New England Journal of Medicine)
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