Disease Information for Interstitial lung disease, chronic

Clinical Manifestations
Signs & Symptoms
Clubbing of fingers/toes
P2 sound accentuated
Bronchospasm signs
Cellophane crackles/rales at bases sign
Cough Chronic
Cough Dry Non-productive
Dyspnea on exertion
Dyspnea, chronic progressive
Exertional cyanosis
Lung signs/abnormality
Pulmonary Crackles
Shortness of breath/SOB
Wheezing in Elderly
Chronically ill patient/signs
Disease Progression
Course/Chronic disorder
Course/Chronic only
Demographics & Risk Factors
Event, Activity, Behavioral & Seasonal Factors
Lifestyle/Drug addiction/population
Diagnostic Test Results
Other Tests & Procedures
PFT/Abnormal pulmonary function tests
PFT/Carbon monoxide diffusion (DLCO)/Abnormal
PFT/Compliance decreased
PFT/Diffusion defect
PFT/DLCO (CO diffusion) Decreased
BX/Lung Abnormal (Biopsy)
BX/Lung biopsy/Interstitial fibrosis
EKG/P Wave > 2.5 mV inferior leads (ECG)
EKG/Incomplete right bundle branch block (ECG)
Xray/Chest abnormal
Xray/Chest/Lung fields/Abnormal
Xray/Diffuse increased markings/fibrosis/Chest
Xray/Honeycomb lung/Chest
Xray/Infiltrate, pulmonary/Chest
Xray/Interstitial edema/Chest
Xray/Interstitial infiltrate/fibrosis/Chest
Xray/Kerley A Lines/Chest
Xray/Kerley lines/Chest film
Xray/Reticular pattern/Chest
Echo/Pulmonary artery hypertension
Associated Diseases & Rule outs
Rule Outs
Bronchiolitis obliterans
Pulmonary Fibrosis, Primary/H-R Disease
Tuberculosis, pulmonary
Associated Disease & Complications
Acidosis, respiratory
Alveolar-capillary block/Diffusion disorder
Atelectasis, pulmonary
Carcinoma, bronchogenic
Cor pulmonale
Interstitial lung involvement/manifestation
Pulmonary hypertension
Pulmonary hypertension, secondary
Pulmonary Interstitial fibrosis, secondary
Disease Mechanism & Classification
CLASS/Primary organ/system disorder (ex)
CLASS/Lung Disorder (ex)
CLASS/Primary lung disease (ex)
CLASS/Pulmonic (category)
Pathophysiology/Chronic intrinsic restrictive lung
Pathophysiology/Exertional O2 desaturation
Pathophysiology/Inflammatory lung disorder (ex)
Pathophysiology/Interstitial lung disorder (ex).
PROCESS/Reference organ/system (category)
chronic, Interstitial lung disease (SMQ), Synonym/CIRLD/Chr intrinsic restrictive lung dis.
Surgical Procedures or Treatments

Pneumonia, Interstitial;Bronchiolitis Obliterans Organizing Pneumonia (Boop);Chronic Fibrous Pneumonia; Diffuse Alveolar Damage; Fibrous Interstitial Pneumonia; Giant Cell Interstitial Pneumonia; Idiopathic Interstitial Pneumonia;

Usual Interstitial Pneumonia (UIP); Acute Interstitial Pneumonia (AIP); Cryptogenic Organizing Pneumonia (COP); Desquamative Interstitial Pneumonia (DIP);

Idiopathic Pulmonary Fibrosis (IPF); Lymphoid Interstitial Pneumonia (LIP); Nonspecific Interstitial Pneumonia (NSIP);

Respiratory Bronchiolitis-Associated Interstitial Lung Disease (RB-ILD); The abnormal accumulation of inflammatory cells in lung tissue may lead to any one of several disorders with similar signs and symptoms; As white blood cells and protein-rich plasma build up in the air sacs of the lungs (alveoli), inflammation is generated; The inflammatory process, if it lasts long enough, may harden the fluid and the resultant firm, fibrous substance (scarring) may replace the lung tissue; If the scarring is extensive, the air sacs may be destroyed over time and the resultant space replaced by cysts; The American Thoracic Society and the European Respiratory Society jointly studied the interstitial pneumonias during 2001 and issued a Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias; This consensus statement was intended to replace several older classification schemes that had led to a confusion of names and syndromes; Participants agreed that the Idiopathic Interstitial Pneumonias (IIPs) comprise a number of clinical entities that are each rare and sufficiently different from one another to be considered as distinct disorders; This report follows the joint ARS/ERS classification-----------[NORD 2005]--------------Interstitial pneumonias are a confusing and frustrating set of diseases both for the treating physician and for the diagnostic pathologist; One source of the confusion has been the lack of overlapping terms that treating physicians and pathologists use; For example, idiopathic pulmonary fibrosis (IPF) is a clinical term describing a slowly progressive, chronic interstitial pneumonia; Since many of the interstitial pneumonias, including UIP, DIP, and NSIP, fall under this category, it is a non-specific term; Most pathologists who are experts in lung pathology use the terms IPF and UIP to mean the same disease process; To complicate matters even further, European clinicians utilize the term cryptogenic fibrosing alveolitis for IPF; Bronchiolitis obliterans with organizing pneunomina (BOOP) is no longer used because it has been considered a mixture of terms; Lymphocytic interstitial pneumonia (LIP) is now considered a lymphoproliferative disease; Giant cell interstitial pneumonitis (GIP) is now considered a hard metal pneumoconiosis; The symptoms vary for each of the pneumonias but most are characterized by a slowly progressive shortness of breath; Chest radiographs reveal a hazy ground glass appearance with linear opacities; Most of the diseases are progressive and are treated with corticosteroids;

----------[DoctorsDoctor-com 2005]-----


External Links Related to Interstitial lung disease, chronic
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)