Disease Information for Interstitial acute lung disease

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Clinical Manifestations
Signs & Symptoms
Bronchospasm signs
Cellophane crackles/rales at bases sign
Cough
Cough Dry Non-productive
Dyspnea
Dyspnea at rest
Dyspnea on exertion
Dyspnea, chronic progressive
Lung signs/abnormality
Pulmonary Crackles
Rales
Shortness of breath/SOB
Wheezing
Wheezing in Elderly
Acutely ill patient/signs
Disease Progression
Course/Acute
Course/Acute only
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Specific Single Nucleotide Polymorphism/SNIP genome type
Diagnostic Test Results
Other Tests & Procedures
Bronchopulmonary alveolar lavage/BAL/Abnormal
PFT/Abnormal pulmonary function tests
PFT/Carbon monoxide diffusion (DLCO)/Abnormal
PFT/Compliance decreased
PFT/Diffusion defect
PFT/DLCO (CO diffusion) Decreased
Pathology
BX/Lung biopsy/Interstitial cell infiltrate
BX/Lung biopsy/Interstitial fibrosis
X-RAY
Xray/Chest abnormal
Xray/Atelectasis/Chest
Xray/Chest/Lung fields/Abnormal
Xray/Diffuse increased markings/fibrosis/Chest
Xray/Ground glass appearance/Chest
Xray/Honeycomb lung/Chest
Xray/Infiltrate, pulmonary/Chest
Xray/Interstitial edema/Chest
Xray/Interstitial infiltrate, acute/Chest
Xray/Interstitial infiltrate/fibrosis/Chest
Xray/Kerley A Lines/Chest
Xray/Kerley lines/Chest film
Xray/Reticular pattern/Chest
Associated Diseases & Rule outs
Rule Outs
Asthma
Bronchiolitis obliterans
Pulmonary Fibrosis, Primary/H-R Disease
Silicosis
Associated Disease & Complications
Acidosis, respiratory
Atelectasis, pulmonary
Hypocapnea/hypocarbia
Interstitial lung involvement/manifestation
Pneumonia, interstitial, acute
Pulmonary Interstitial fibrosis, secondary
Respiratory distress (adult) syndrome
Disease Mechanism & Classification
Class
CLASS/Lung Disorder (ex)
CLASS/Pulmonic (category)
Pathophysiology
Pathophysiology/Inflammatory lung disorder (ex)
Pathophysiology/Interstitial lung disorder (ex).
Process
PROCESS/Reference organ/system (category)
Definition

Pneumonia, Interstitial;Bronchiolitis Obliterans Organizing Pneumonia (Boop);Chronic Fibrous Pneumonia; Diffuse Alveolar Damage; Fibrous Interstitial Pneumonia; Giant Cell Interstitial Pneumonia; Idiopathic Interstitial Pneumonia;

Usual Interstitial Pneumonia (UIP); Subdivisions: Acute Interstitial Pneumonia (AIP); Cryptogenic Organizing Pneumonia (COP); Desquamative Interstitial Pneumonia (DIP);

Idiopathic Pulmonary Fibrosis (IPF); Lymphoid Interstitial Pneumonia (LIP); Nonspecific Interstitial Pneumonia (NSIP);

Respiratory Bronchiolitis-Associated Interstitial Lung Disease (RB-ILD); The inflammatory process, if it lasts long enough, may harden the fluid and the resultant firm, fibrous substance (scarring) may replace the lung tissue; If the scarring is extensive, the air sacs may be destroyed over time and the resultant space replaced by cysts; The Idiopathic Interstitial Pneumonias (IIPs) comprise a number of clinical entities that are each rare and sufficiently different from one another to be considered as distinct disorders; [NORD 2005]----------------------------------------------.Interstitial pneumonias are a confusing and frustrating set of diseases both for the treating physician and for the diagnostic pathologist; One source of the confusion has been the lack of overlapping terms that treating physicians and pathologists use; For example, idiopathic pulmonary fibrosis (IPF) is a clinical term describing a slowly progressive, chronic interstitial pneumonia; Since many of the interstitial pneumonias, including UIP, DIP, and NSIP, fall under this category, it is a non-specific term; Most pathologists who are experts in lung pathology use the terms IPF and UIP to mean the same disease process; To complicate matters even further, European clinicians utilize the term cryptogenic fibrosing alveolitis for IPF; Pathologists also share in the confusion; Bronchiolitis obliterans with organizing pneunomina (BOOP) is no longer used because it has been considered a mixture of terms; Lymphocytic interstitial pneumonia (LIP) is now considered a lymphoproliferative disease; Giant cell interstitial pneumonitis (GIP) is now considered a hard metal pneumoconiosis; The symptoms vary for each of the pneumonias but most are characterized by a slowly progressive shortness of breath; Chest radiographs reveal a hazy ground glass appearance with linear opacities; Most of the diseases are progressive and are treated with corticosteroids;-----------[DoctorsDoctor-com 2005]--------

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External Links Related to Interstitial acute lung disease
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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