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Disease Information for Interferon alfa-2b (Intron/A) Administration/Toxicity

Clinical Manifestations

Signs & Symptoms

Muscle Pain

Myalgias

Tender or painful muscles/Myalgias

Malaise

Laboratory Tests

Abnormal Lab Findings (Non Measured)

Leukopenia

Abnormal Lab Findings - Decreased

Platelet count (Lab)

Associated Diseases & Rule outs

Associated Disease & Complications

Alpha-interferon effect/toxicity

Depression

Drug induced Depression

Thrombocytopenia

Disease Mechanism & Classification

Drugs

DRUG/ Source rDNA Manufacture

DRUG/Antibiotic/Antimicrobial drugs (category)

DRUG/Antiviral medication (example)

DRUG/Biological response modifiers/chemoRX (example)

DRUG/Biologicals/serums/vaccines/blood products (cat)

DRUG/Genetically engineered/biological drug (example)

DRUG/Immune response modifier effect

DRUG/Interferon preparation (ex)

Process

PROCESS/Medication/Drug (CONFIRM dose/before treatment)

Synonyms

Synonym

IFN alpha 2B, Inteferon alpha 2b (human leukocyte clone Hif SN 206 protein moiety reduced), INTERFERON, INTERFERON ALFA 2 B, INTERFERON ALFA 2 B PREPARATION, Interferon alfa 2b, INTERFERON ALFA 2B PREPARATION, Interferon Alfa 2b Recomb, Interferon Alfa 2b Recombinant, INTERFERON ALFA 2B RECOMBINANT PREPARATION, INTERFERON ALFA B 02, interferon alpha 2b, Interferon alpha 2b (substance), Interferon alpha 2b preparation, Interferon alpha 2b preparation (product), Interferon alpha 2b preparation (substance), Interferon alpha 2b Recombinant, Recombinant Interferon Alfa 2b, RECOMBINANT INTERFERON ALFA B 02, Recombinant Interferon alpha 2b, Brand name/Intron-A (Interferon alpha 2b), Brand name/Peg-Intron (Peginterferon alfa-2b), Brand name/Rebetron (comb)

Treatment

Drug Dosage

DRUG/.$$$$$ Most Expensive

DRUG/Injectable medication (parenteral)

DRUG/Injectable preparation only

Definition

Interferon recombinant as interferon alfa-2b (also pegelated preparation as PEG-Intron-A);subcutaneous preparation used for chronic hepatitis C and B; Also used for AIDS Kaposis sarcoma,hairy cell leukemia, malignant melanoma, and follicular lymphoma

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External Links Related to Interferon alfa-2b (Intron/A) Administration/Toxicity

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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