Disease Information for Infiltrative cardiomyopathy

Ads
Clinical Manifestations
Signs & Symptoms
PMI Displaced Lateral
Abnormal Heart Sounds
Abnormal Heart Sounds/Child
Cardiac Symptoms/Signs
Gallop,Ventricular/S3 Sound
Irregular rhythm/heartbeat
Third Heart Sound/S3 prominent
Demographics & Risk Factors
Established Disease Population
Patient/Hemochromatosis
Diagnostic Test Results
Other Tests & Procedures
Cardiac index reduced
Pathology
BX/Endomyocardial Biopsy Abnormal
BX/Myocardial biopsy/abnormal
Isotope Scan
Isotope/Cardiac Tch99 Pyrophosphate scan Abnormal
MUGA Scan/Cardiac abnormal
MUGA scan/cardiac output decreased
EKG (ECG)
EKG/Pseudoinfarction pattern/Q Waves/atypical (ECG)
EKG/AV Nodal Block/Complete
EKG/Interventricular block/non-specific (ECG)
EKG/Left bundle branch block,complete (ECG)
EKG/Changes/abnormalities (ECG)
X-RAY
Fluoroscopy/Heart decreased pulsation/force
Fluoroscopy/Ventricular pulse diminished force
Xray/Cardiomegaly/Chest
Ultrasound
Echo/Echocardiogram Abnormal
Echo/Hypokinesis Zones
Echo/Stiff ventricular wall motion
Echo/Trans-esophageal echocardiograph/abnormal (TEE)
Associated Diseases & Rule outs
Rule Outs
Amyloidisis, heart
Cardiomyopathy, congested
Myocarditis
Myocarditis, acute
Tamponade, cardiac/pericardial
Associated Disease & Complications
AV node lesion/infiltrate
Heart block, complete
Infiltrative cardiomyopathy
Ischemia, cardiac
Left bundle branch block
Left Ventricular Failure
Disease Mechanism & Classification
Class
CLASS/Cardiovascular (category)
CLASS/Heart disorder (ex)
CLASS/Myocardial involvement/disorder (ex)
Pathophysiology
Pathophysiology/Infiltrative process
Pathophysiology/Myocardial infiltrate/Infiltrative (ex)
Pathophysiology/Myocardial Ischemia Functional
Process
PROCESS/Complicating disorder (ex)
PROCESS/Pathophysiology/organ-system (category)
Definition

restrictive cardiomyopathy infiltrative; Cardiomyopathy, Restrictive (PTG); Fred F Ferri MD; Cardiomyopathies are a group of diseases primarily involving the myocardium and characterized by myocardial dysfunction that is not the result of hypertension, coronary atherosclerosis, valvular dysfunction, or pericardial abnormalities; Restrictive cardiomyopathies are characterized by decreased ventricular compliance, usually secondary to infiltration of the myocardium; This is a relatively less cardiomyopathy that is most frequently caused by amyloidosis, myocardial fibrosis (after open heart surgery), and radiation, also hemochromatosis, sarcoidosis, and endomyocardial eosinophilia; CLINICAL PRESENTATION :Edema, ascites, hepatomegaly, distended neck veins ,Fatigue, weakness (secondary to low output) Kussmaul’s sign: may be present

Regurgitant murmurs; Possible prominent apical impulse

Infiltrative and storage disorders (glycogen storage disease, amyloidosis, sarcoidosis, hemochromatosis)

Scleroderma; Radiation; Endocardial fibroelastosis; Endomyocardial fibrosis; Idiopathic; Toxic effects of anthracycline; Carcinoid heart disease, metastatic cancers

Diabetic cardiomyopathy; Eosinophilic cardiomyopathy (Löffler’s endocarditis; Moderate cardiomegaly on X-ray CHF (pulmonary vascular congestion, pleural effusion); ECG: Low voltage with ST-T wave changes; frequent arrhythmias, left axis deviation, and atrial fibrillation; Echocardiogram: increased wall thickness and thickened cardiac valves (especially in patients with amyloidosis);Cardiac catheterization to distinguish restrictive cardiomyopathy from constrictive pericarditis ;Constrictive pericarditis: usually involves both ventricles and produces a plateau of elevated filling pressures; Restrictive cardiomyopathy: impairs the left ventricle more than the right (PCWP > RAP, PASP >50 mm Hg) MRI may also be useful to distinguish restrictive cardiomyopathy from constrictive pericarditis (thickness of the pericardium >5 mm in the latter)

[merck medicus website ferri clinical advisor 2005]

(Edit)

External Links Related to Infiltrative cardiomyopathy
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
Ads