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- Disease Information
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Disease Information for Inappropriate ADH secretion
- Clinical Manifestations
- Signs & Symptoms
- Intracutaneous edema signs
- Anorexia Decreased appetite
- Nausea
- Vomiting
- Weight gain in Elderly
- Cramping in Extremities
- Altered mental status Mental status change
- Confusion/Disoriented
- Headache
- Hyporeflexia/DTRs decreased
- Irritability/short tempered
- Lethargy/torpor
- Neurologic manifestations/signs
- Seizures
- Sudden unconsciousness
- Unconscious/Narcosis status
- Weak reflexes
- Weight gain
- Clinical Presentation & Variations
- Presentation/Confusion Elderly Postop Low Sodium
- Demographics & Risk Factors
- Established Disease Population
- Patient/Surgical procedures recent
- Patient/Hypothyroidism (myxedema)
- Occupational Factors
- Setting/Hospital setting
- Sex & Age Groups
- Population/Adult Aged Only
- Population/Adult/all
- Population/Sixties-adult
- Laboratory Tests
- Abnormal Lab Findings - Decreased
- Albumin, serum (Lab)
- BUN/Blood urea nitrogen (Lab)
- BUN/Creatinine ratio (Lab)
- Calcium, serum (Lab)
- Chloride serum (Lab)
- Gamma globulin (Lab)
- Globulin, serum (Lab)
- Magnesium (Lab)
- Osmolality, serum (Lab)
- Potassium, serum (Lab)
- Sodium, serum (Lab)
- Uric acid, serum (Lab)
- Abnormal Lab Findings - Increased
- ADH/Antidiuretic Hormone/Vasopressin/Oxytocin level (Lab)
- URINE Osmololality
- URINE Sodium
- URINE Specific gravity
- Diagnostic Test Results
- Other Tests & Procedures
- TEST/Plasma Volume measurement/increased
- Associated Diseases & Rule outs
- Rule Outs
- Cerebral salt-wasting syndrome
- Hypogammaglobulinemia
- Hypothalamic dysfunction
- Associated Disease & Complications
- Coma/Unconscious
- Convulsions (grand mal)
- Hallucinations
- Hypoalbuminemia Hypoproteinemia
- Hypocalcemia
- Hypokalemia
- Hypomagnesemia
- Hyponatremia
- Hypo-Osmolar State
- Hypouricemia
- Inappropriate ADH secretion syndrome
- Magnesium deficiency
- SIADH, idiopathic
- Water retention
- Disease Synergy - Causes
- Synergy/Post Operative-Recent Surgery
- Disease Mechanism & Classification
- Class
- CLASS/Endocrine gland (category)
- CLASS/Hypothalamus/neurohypophysis involvement (ex)
- Pathophysiology
- Pathophysiology/High extracellular fluid volume
- Pathophysiology/Volume redistribution
- Pathophysiology/Paraneoplastic Endocrine Syndrome exists
- Process
- PROCESS/Endocrine/humoral disorders (category)
- PROCESS/Vegetative-Autonomic/Endocrine (category)
- Synonyms
- Synonym
- ADH INAPPROPRIATE, ADH inappropriate secretion, ADH Syndrome Inappropriate, ANTIDIURETIC HORMONE INAPPROPRIATE SECRET, Antidiuretic Hormone Inappropriate Secretion, antidiuretic hormone inappropriate secretion (SIADH), ANTIDIURETIC HORMONE INAPPROPRIATE SECRETION SYNDROME (SIADH), ANTIDIURETIC HORMONE INAPPROPRIATE SECRETION SYNDROME SIADH, antidiuretic hormone syndrome (SIADH), hormone secretion antidiuretic inadequate (syndrome), hormone secretion antidiuretic inappropriate (syndrome), inadequate secretion antidiuretic hormone (syndrome), Inapprop ADH secretion syndrome, Inappropriate ADH, inappropriate ADH secretion, Inappropriate ADH syndrome, Inappropriate anti diuretic hormone syndrome, Inappropriate antidiuretic hormone secretion, Inappropriate Antidiuretic Hormone Secretion Syndrome, INAPPROPRIATE SECRETION OF ANTIDIURETIC HORMONE, inappropriate secretion of antidiuretic hormone syndrome, INAPPROPRIATE VASOPRESSIN SECRET SYNDROME, Inappropriate vasopressin secretion, Inappropriate Vasopressin Secretion Syndrome, Schwartz Bartter Syndrome, Schwarz Bartter syndrome, secretion hormone antidiuretic inappropriate (syndrome), SIAD Syn inappr antidiuresis, SIAD Syndrome of inappropriate antidiuresis, SIADH, SIADH Synd inappr secret ADH, SIADH Syndrome of inappropriate secretion of ADH, SIADH Syndrome of inappropriate secretion of antidiuretic hormone, SIADH (syndrome of inappropriate secretion of antidiuretic hormone), Syndrome inappr secretion ADH, Syndrome inapprop antidiuresis, Syndrome inappropriate ADH, SYNDROME INAPPROPRIATE ADH SIADH SECRET, SYNDROME INAPPROPRIATE ANTI DIURETIC HORMONE, syndrome inappropriate secretion of antidiuretic hormone, SYNDROME OF INAPP ADH SECRETION, Syndrome of Inappropriate ADH (SIADH) Secretion, Syndrome of inappropriate ADH production, Syndrome of inappropriate antidiuresis, SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE, Syndrome of Inappropriate Antidiuretic Hormone Secretion, Syndrome of inappropriate secretion of ADH, Syndrome of inappropriate secretion of antidiuretic hormone, Syndrome of inappropriate vasopressin secretion, Syndrome of inappropriate vasopressin secretion (disorder), Syndrome Schwartz Bartter, Synonym/Cerebral hyponatremia syndrome, Synonym/Cerebral salt-wasting syndrome, Synonym/Schwartz-Bartter syndrome, Synonym/SIADHS
- Treatment
- Drug Therapy - Indication
- RX/Demeclocycline (Declomycin)
- RX/Tolvaptan (Samsca)
- Other Treatments
- TX/Fluid restriction
- Definition
-
Hyponatremia and renal salt loss attributed to overexpansion of body fluids resulting from sustained release of VASOPRESSINS (i.e., antiduretic hormone) despite the absence of appropriate stimuli. Associated conditions include medication effect; MENINGITIS; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; CEREBROVASCULAR DISORDERS; HYDROCEPHALUS; PNEUMONIA; ASTHMA; THYROID DISEASES; and other conditions. This condition may also be idiopathic or result from ectopic (extra-pituitary) production of ADH. (From Joynt, Clinical Neurology, 1992, Ch36, pp59-62)
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- External Links Related to Inappropriate ADH secretion
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- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)