Disease Information for Hypertrophic osteoarthropathy/pulmonic

Clinical Manifestations
Signs & Symptoms
Furrowed forehead
Clubbing of fingers/toes
Excess feet sweating
Grooves/Depressions in Scalp
Hyperhidrosis/Chronic sweating excess
Pachyderma Facial Skin
Scalp rash/Oily scales/pruritic
Sweating Excess Perspiration
Thickened skin/diffuse
Hand Pains
Hip Inner Thigh Pain
Leg/lower extremity pains
Pain in Extremities/Melalgias
Sweating palms
Arthralgias Polyarthralgias
Bone Pains
Hip Pain
Joint deformities
Joint effusion
Joint Pains
Joint pains Arthralgias in Elderly
Joint Swelling
Knee Pain
Monoarticular Arthritis/One joint acute
Multiple Joint Arthritis
Periosteal Mass
Periosteitis Distal Ulna Radius Tibia
Polyarticular Joint Pain
Single Joint Pain
Skeletal problems/symptoms/signs
Tender Bones (Long Bones)
Coarsened facial features
Typical Clinical Presentation
Males sicker than females/characteristic
Demographics & Risk Factors
Ethnic or Racial Factors
Black/African american population
Established Disease Population
Patient/Cystic fibrosis
Population Group
Middle Age Adult
Sex & Age Groups
Population/Fifties adult
Population/Middle-aged adult
Diagnostic Test Results
Isotope Scan
Isotope/Bone scan abnormality
Xray/Chest abnormal
Xray/Chest/Lung fields/Abnormal
Xray/Enlarged sinuses/Head
Xray/Skeletal findings
Xray/Subperiosteal new bone growth/diffuse
Associated Diseases & Rule outs
Rule Outs
Polyarthritis syndrome/Multiple joints/weeks
Polyarthritis, carcinomatous
Associated Disease & Complications
Arthropathy, reactive (post-infectious)
Dermatitis/Chronic rash
Hypertrophic osteoarthropathy
Osteoarthropathy, hypertrophic primary
Polyarthritis syndrome/Multiple joints/weeks
Seborrhea/Seborrhea dermatitis
Monoarthritis Acute
Disease Mechanism & Classification
CLASS/Lung manifestions/involvement/secondary (ex)
CLASS/Bone disorder (ex)
CLASS/Joint disorder (ex).
CLASS/Skeletal (category)
PROCESS/Hypertrophic/Hyperplastic disorder (ex)
PROCESS/INCIDENCE/Rare disease (ex)
PROCESS/Inflammatory/Traumatic/regeneration (ex)
PROCESS/Paraneoplastic disorder (ex)
PROCESS/Reference organ/system (category)
PROCESS/Vegetative-Autonomic/Endocrine (category)
Acropachy, Bamberger Marie, Bamberger Marie disease, Disease Marie Bamberger, HPOA Hypert pulm osteoarthr, HPOA Hypertrophic pulmonary osteoarthropathy, Hypertroph pulmon osteoarthrop, Hypertrophic Osteoarthropathies Secondary, hypertrophic osteoarthropathy pulmonary, HYPERTROPHIC OSTEOARTHROPATHY SECOND, Hypertrophic Osteoarthropathy Secondary, Hypertrophic Pulmonary Osteoarthropathy, Hypertrophic pulmonary osteoarthropathy (disorder), Marie Bamberger, MARIE BAMBERGER DIS, Marie Bamberger Disease, Osteoarthropathies Secondary Hypertrophic, osteoarthropathy hypertrophic pulmonary, Osteoarthropathy hypertrophic secondary, OSTEOARTHROPATHY SECOND HYPERTROPHIC, Osteoarthropathy Secondary Hypertrophic, Pachydermoperiostitis acquired, Pulmonary osteoarthropathy hypertrophic, SECOND HYPERTROPHIC OSTEOARTHROPATHY, Secondary Hypertrophic Osteoarthropathies, Secondary hypertrophic osteoarthropathy, secondary osteoarthropathy hypertrophic, Synonym/Bamberger-Marie disease, Synonym/Hypertrophic Clubbing Synd, Synonym/Marie-Bamberger disease, Synonym/Pachydermoperiostosis, secondary, Synonym/Pulmonary osteoarthropathy, hypertrophic
Drug Therapy - Indication
RX/Non-steroidal anti-inflammatory drugs
RX/Prednisone (Deltasone)
Surgical Procedures or Treatments
SX/Vagotomy Indications
Other Treatments
TX/Expectant/supportive treatment.

Hypertrophic osteoarthropathy (HOA) is a syndrome of clubbing of the digits, periostitis of long bones, and arthritis; HOA may be primary or secondary to other underlying disease processes; Secondary hypertrophic osteoarthropathy; Hypertrophic osteoarthropathy; Secondary HOA typically occurs in adults and is associated with other illnesses including: Pulmonary: Bronchogenic carcinoma, lung abscess,bronchiectasis, cystic fibrosis, pulmonary fibrosis, mesothelioma, sarcoidosis; Gastrointestinal: Esophageal carcinoma, colon cancer,inflammatory bowel disease (Crohn"s disease, ulcerative colitis), hepatocellular carcinoma, liver cirrhosis, amebiasis; Cardiac: Infective endocarditis, right-to-left cardiac shunts, aortic aneurysm; Thymoma; Lymphoma ; Connective tissue diseases; signs and symptoms include:Joint pain and swelling; Decreased use of the fingers and hands; Facial changes, coarse facial skin grooves; Thickening of the arms and legs; Oily skin, diaphoresis, gynecomastia, and acne; Secondary HOA patients may present with clinical symptoms before the underlying disorder can be detected. Signs and symptoms are similar to the above mentioned in addition to findings related to the underlying disease; (eg, bronchogenic carcinoma, infective endocarditis); [Ferri Clinical advisor 2005];-----------------------------------------------Hypertrophic osteoarthropathy is divided into primary and secondary forms; Pachydermoperiostosis (PDP), the primary form, accounts for 5% of all cases of hypertrophic osteoarthropathy; Secondary hypertrophic osteoarthropathy,also called pulmonary hypertrophic osteoarthropathy, is associated with underlying cardiopulmonary diseases and malignancies; characterized by digital clubbing and subperiosteal new bone formation associated with pain, polyarthritis, cutis verticis gyrata, seborrhea, and hyperhidrosis; Pachydermia of the facial skin and/or scalp) and periostitis, PDP is more common in African Americans than in whites; The male-to-female case ratio is approximately 7:1;

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External Links Related to Hypertrophic osteoarthropathy/pulmonic
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)