Disease Information for Hyperprolactinemia

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Clinical Manifestations
Signs & Symptoms
Breast Discharge
Breast engorgement
Breast enlargement
Breast Swelling Bilateral
Galactorrhea/Male
Lactorrhea in a male
Lactorrhea/Galactorrhea/Prolonged lactation
Nipple discharge/Nipple lesion
Delayed male adolescence/pubescence
Impotence, relative
Loss of libido,male
Sexual dysfunction
Amenorrhea
Amenorrhea, primary
Amenorrhea, secondary
Oligomenorrhea/Hypomenorrhea
Uterine Bleeding
Weight gain
Disease Progression
Galactorrhea
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Hyperprolactinemia
Abnormal Lab Findings - Decreased
Androgens (Lab)
Estrogen, serum (Lab)
Testosterone Total (Lab)
Abnormal Lab Findings - Increased
Prolactin (Lab)
Diagnostic Test Results
CT Scan
CT Scan/Bone densometry/density decreased
CT/Dexa-Scan Bone density Abnormal
Associated Diseases & Rule outs
Associated Disease & Complications
Colostrum flow/breast
Dysfunctional Uterine Bleeding
Gonadotropin deficiency/Female acquired
Gynecomastia
Hypogonadism, male
Impotence/Erectile dysfunction disorder
Infertility/sterility male
Infertility/sterility, female
Male osteoporosis syndrome
Osteoporosis/osteopenia
Pathologic fractures
Metabolic Bone Disease
Disease Mechanism & Classification
Pathophysiology
Pathophysiology/Release from tonic dopamine neurohypophysis
Pathophysiology/Secondary Testicular Failure
Pathophysiology/Osteoporosis Secondary
Treatment
Drug Therapy - Indication
RX/Cabergoline (Dostinex)
Definition

Increased levels of prolactin in the blood, which may be associated with AMENORRHEA and GALACTORRHEA. Relatively common etiologies include PROLACTINOMA, medication effect, KIDNEY FAILURE, granulomatous diseases of the pituitary gland, and disorders which interfere with the hypothalamic inhibition of prolactin release. Ectopic (non-pituitary) production of prolactin may also occur. (From Joynt, Clinical Neurology, 1992, Ch36, pp77-8)

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External Links Related to Hyperprolactinemia
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NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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