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- Disease Information
- Disease Comparison
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Disease Processes ▼
- Auto Immune
- Vascular-Arteriosclerosis
- Biochemical
- Congenital-developmental
- Deficiency
- Degenrative-Necrosis
- Electromagnetic-Physics
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Major Organs-Systems ▼
- Systemic
- Pediatric
- Nervous & Sensory System (Neurology)
- Cardiovascular System
- Respiratory (Pulmonary) System
- Gastro-Intestinal (Digestive) System
- Urinary System
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- Endocrine System
- Immune System
- Musculoskeletal System
- Genital Reproductive System
- Hematopoietic System (Hematology)
- Lymphatic System
- Tissue/Cells/Organelles
Disease Information for Hypereosinophilic syndrome
- Clinical Manifestations
- Signs & Symptoms
- Chest Pain
- Red/erythema skin discoloration
- Erythroderma
- Fever and Rash
- Hyperhidrosis/Chronic sweating excess
- Night sweats
- Pruritis Itching
- Rash
- Sweating Excess Perspiration
- Symmetrical rash
- Abdominal Pain
- Abdominal Pain Crampy
- Anorexia Decreased appetite
- Palpable Liver/Hepatomegaly
- Dysesthesias
- Chest pain/non-cardiac
- Cough
- Cough Chronic
- Dyspnea
- Arthritis with Fever
- Splenomegaly
- Fever
- Fever Febrile Possible
- Fever of unknown origin/chronic fever
- Flu-Like Syndrome
- High body temperature
- Malaise
- Weight Loss
- Disease Progression
- Course/Chronic disorder
- Course/Subacute
- Onset/insidious
- Demographics & Risk Factors
- Sex & Age Groups
- Population/Male
- Laboratory Tests
- Microbiology & Serology Findings
- Stool Microscopic polys present
- Abnormal Lab Findings (Non Measured)
- Acute inflammatory markers elevated (Lab)
- Eosinophilic leukemoid reaction (Lab)
- Extreme eosinophilia (Lab)
- Abnormal Lab Findings - Decreased
- Hematocrit (Lab)
- Hemoglobin (Lab)
- RBC/Red Blood Count (Lab)
- Abnormal Lab Findings - Increased
- Eosinophiles (LAB)
- WBC
- IGE/Immunoglobulin E (Lab)
- WBC/White Blood Cell Count/Leukocytes (Lab)
- Diagnostic Test Results
- Pathology
- BX/Myocardial biopsy/cellular infiltrate
- PATH/Myocardial eosinophilic infiltrate
- BX/Skin biopsy/eosinophile infiltrate
- Bone Marrow/Eosinophilia/adult forms
- Bone Marrow/Ratio myeloproliferative increase
- PATH/Eosinophilic infiltrate/tissue
- EKG (ECG)
- EKG/Non-specific ST-T Wave changes (ECG)
- X-RAY
- Xray/Cardiomegaly/Chest
- Xray/Chest abnormal
- Xray/Chest film/extrapulmonary abnormal
- Xray/Chest/Lung fields/Abnormal
- Xray/Infiltrate, pulmonary/Chest
- Xray/Pulmonary fibrosis/Chest
- Xray/Pulmonary infiltrate eosinophilia (PIE/Loeffler's syndrome)
- Associated Diseases & Rule outs
- Rule Outs
- Behcet's syndrome
- Churg Strauss pulmonary vasculitis
- Eosinophilia, tropical
- Eosinophilia-polymyalgia syndrome
- Eosinophilic pneumonia/prolonged
- Leukemia, eosinophilic
- Loefflers/Eosinophilic pneumonia, acute
- Polyarteritis nodosa
- Associated Disease & Complications
- Acquired valvular heart disease
- Anemia
- AV node lesion/infiltrate
- Bradyarrhythmias
- Cardiomyopathy, end stage
- Congestive heart failure
- Death/Unanticipated
- Eosinophilia Hypereosinophilia
- Eosinophilic pneumonia/prolonged
- Heart block, complete
- Leukemoid reaction
- Leukocytosis
- Loeffler's endocarditis
- Mononeuritis, multiplex
- Multi-radicular Polyneuropathy syndrome
- Mural thrombosis, heart
- Myocardial conduction abnormalities
- Peripheral neuropathy
- Polyneuritis
- Pulmonary eosinophilia syndrome
- Pulmonary fibrosis
- Polyneuropathy
- Disease Mechanism & Classification
- Class
- CLASS/Hematologic (category)
- Pathophysiology
- Pathophysiology/Myocardial infiltrate/Infiltrative (ex)
- Pathophysiology/Exertional O2 desaturation
- Pathophysiology/FIP1L1-PDGFRc1 fusion mutation
- Pathophysiology/Tissue infiltrate
- Process
- PROCESS/Allergy/collagen/autoimmune (category)
- PROCESS/Neoplastic (category)
- PROCESS/Paraneoplastic disorder (ex)
- Treatment
- Drug Therapy - Indication
- RX/Corticosteroid (Cortisone)
- RX/Hydroxyurea (Hydrea)
- RX/Imatinib (Gleevec/Glivec)
- RX/Vincristine (Oncovin)
- Definition
-
A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of eosinophils in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs. It is often referred to as idiopathic.
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- External Links Related to Hypereosinophilic syndrome
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)