Disease Information for Hepatic vein occlusion/thrombus

Hepatic vein thrombosis occurs in cancer patients, pregnancy, oral contraceptives, thrombophilia states including nocturnal hemoglobinuria; can be insidious portal hypertension, ascites,jaundice,cirrhosis; or acutely with epigastric pain,shock, (also portal vein thrombosis;may need liver transplant.------------------------------------------------Budd Chiari Syndrome

Budd"s Syndrome

Chiari"s Disease

Chiari-Budd Syndrome

Hepatic Veno-Occlusive Disease

Rokitansky"s Disease

Disorder Subdivisions

General Discussion

Budd-Chiari syndrome is a rare disorder characterized by narrowing and obstruction (occlusion) of the veins of the liver (hepatic veins). Symptoms associated with Budd Chiari syndrome include pain in the upper right part of the abdomen, an abnormally large liver (hepatomegaly), and/or accumulation of fluid in the space (peritoneal cavity) between the two layers of the membrane that lines the stomach (ascites). Additional findings that may be associated with the disorder include nausea, vomiting, and/or an abnormally large spleen (splenomegaly). The severity of the disorder varies from case to case, depending upon the site and number of affected veins. In some cases, if the major hepatic veins are involved, high blood pressure in the veins carrying blood from the gastrointestinal (GI) tract back to the heart through the liver (portal hypertension) may be present. In most cases, the exact cause of Budd-Chiari syndrome is unknown.[NORD 2005]---------------------.

Also known as:

Budd"s disease

Budd"s jaundice

Chiari’s disease

Chiari’s syndrome

Rokitansky’s disease

von Rokitansky disease

Synonyms:

Acute parenchymatous jaundice, acute yellow atrophy of the liver, hepatic vein thrombosis, post-necrotic cirrhosis of the liver

Associated persons:

George Budd

Hans Chiari

Karl Freiherr von Rokitansky

Description:

A rare disorder marked by cirrhosis of the liver and ascites due to an obstruction of the hepatic vein by a blood clot or tumor. Characteristically the caudate lobe of the liver is spared due to direct venous channels from the inferior vena cava. Clinical symptoms include hepatomegaly, sudden abdominal epigastric pain with nausea and vomiting, and ascites. Associated disorders usually include jaundice, haematemesis, leg oedema, oesophageal varices, thrombophlebitis of the inferior vena cava, and portal hypertension. Occurs in an acuta and an intermittent form. More common in males.[whonamedit.com 2005]

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