Disease Information for Hemoglobin S/C disease

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Clinical Manifestations
Signs & Symptoms
Splenomegaly
Fatigue Tiredness in Children
Eye symptoms/signs
Retinal lesions
Disease Progression
Course/Chronic disorder
Course/Chronic only
Demographics & Risk Factors
Population Group
Child
Population/Pediatrics population
Family History
Family history/Anemia
Sex & Age Groups
Population/Child
Population/Child-Infant Only
Population/Children/all
Laboratory Tests
Microbiology & Serology Findings
Reticulocytosis
Abnormal Lab Findings (Non Measured)
Hemoglobin crystals/RBCs smear (Lab)
Hemoglobin electrophoresis abnormal (Lab)
Indirect bilirubin inc/normal direct bil. (Lab)
Microcytes/small RBCs on Blood smear
Microcytosis/microcytic anemia (Lab)
Normocytic Anemia/High Retic count
Abnormal Lab Findings - Decreased
MCV/Mean Corpuscular Volume (Lab)
Abnormal Lab Findings - Increased
Bilirubin, serum (Lab)
Fetal hemoglobin (Lab)
Free hemoglobin, plasma (Lab)
Indirect bilirubin (Lab)
Lactic Dehydrogenase (LDH LH) (Lab)
Polychrome RBCs (Lab)
Reticulocytes (Lab)
Sickle cells/Prep (Lab)
Target cells (Lab)
Associated Diseases & Rule outs
Rule Outs
Paroxysmal cold hemoglobinuria
Associated Disease & Complications
Anemia
Bilirubinemia
Hemolytic anemia, congenital
Retinitis
Disease Synergy - Causes
Synergy/High altitude
Synergy/Pregnancy
Disease Mechanism & Classification
Class
CLASS/Erythrocyte disorder (ex)
CLASS/Hematologic (category)
Pathophysiology
Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
Pathophysiology/Malaria resistant host
Process
PROCESS/Hereditofamilial (category)
PROCESS/Hemoglobinopathy disorder (ex)
PROCESS/Molecular/hematologic disorder (ex)
Definition

One of the sickle cell disorders characterized by the presence of both hemoglobin S and hemoglobin C. It is similar to, but less severe than sickle cell anemia.

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External Links Related to Hemoglobin S/C disease
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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