Disease Information for Hemifacial spasm (Meige's)

Clinical Manifestations
Signs & Symptoms
Unilateral symptoms/signs/findings
Facial hemihypertrophy
Facial muscle spasms
Risus sardonicus
Facial muscle wasting/sign
Associated Diseases & Rule outs
Rule Outs
Associated Disease & Complications
Disease Mechanism & Classification
CLASS/Facial area manifestation/disorder (ex)
CLASS/Neurologic (category)
Pathophysiology/Unilateral effects
PROCESS/Vegetative-Autonomic/Endocrine (category)

Recurrent clonic contraction of facial muscles, restricted to one side. It may occur as a manifestation of compressive lesions involving the seventh cranial nerve (FACIAL NERVE DISEASES), during recovery from BELL PALSY, or in association with other disorders; (From Adams et al, Principles of Neurology )-----------------------------

Hemifacial Spasm (Meige"s Syndrome); Hemifacial spasms are characterized by chronic twitching or spasms of one side of the face; It affects muscles activated by the facial nerve; Hemifacial spasm can result from stimulation by a blood vessel lying too close to the nerve or may follow Bell"s palsy (an inflammation of the facial nerve resulting in temporary facial weakness) due to incorrect regeneration of the facial nerve;In more severe cases, the spasms may cause the mouth to become clamped shut; This can make speaking, eating, and swallowing difficult; Meige"s Syndrome is a similar disorder affecting the long facial muscles and neck muscles in addition to the muscles around the eyes; As with almost any medical procedure, there can be side effects of Botulinum toxin injections. Some people may develop a drooping eyelid, double vision, or dryness of the eye. Fortunately, these side effects wear off with time. ----------[Steen eye institute website 2005]--------

Meige Syndrome; Brueghel Syndrome; Idiopathic Blepharospasm-Oromandibular Dystonia Syndrome; Segmental Cranial Dystonia

Meige Syndrome is a rare neurological movement disorder (dyskinesia) characterized by spasms of the muscles of the eyelids and associated loss of tone in these eyelid muscles;Symptoms may include excessive blinking (blepharospasm) or involuntary eyelid closure; On occasion, the muscles of the face may also be involved;

The exact cause of Meige Syndrome is not known; This disorder generally affects people during late middle age;--------------[NORD 2005]--------------


External Links Related to Hemifacial spasm (Meige's)
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)