Disease Information for Hand-Schuller-Christian syndrome

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Clinical Manifestations
Signs & Symptoms
Dandruff
Delayed female adolescence
Gingival swelling
Loose teeth/falling out
Precocious teeth eruption/child
Lymphadenopathy Systemic
Proptosis,bilateral
Proptosis,unilateral
Clinical Presentation & Variations
Presentation/Triad DI Exophthalmous Bone lesions
Disease Progression
Course/Chronic disorder
Course/Chronic only
Demographics & Risk Factors
Population Group
Child
Population/Pediatrics population
Sex & Age Groups
Population/Boy patient
Population/Child
Population/Child-Infant Only
Population/Children/all
Population/Preschool child
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Hyperprolactinemia
Abnormal Lab Findings - Increased
Prolactin (Lab)
Diagnostic Test Results
Pathology
BX/Lung biopsy/Granulomas in lung
BX/Bone biopsy/abnormal
PATH/Langerhans' histiocyte/Birbeck granules/electronmicr
PATH/Langerhans' histiocyte/CD1 cell surface
PATH/Langerhans' histiocyte/Immune S100 protein
PATH/Langerhans' histiocyte/Pale distinct/abundant cytoplasm
PATH/Langerhans' histiocytes present
PATH/Langerhans' histiocytes/Coffee bean nucleus
CT Scan
MRI/Orbits abnormality
X-RAY
Xray/Chest abnormal
Xray/Auditory meatus widened or eroded/Skull
Xray/Chest/Lung fields/Abnormal
Xray/Lung lesion/localized/Chest
Xray/Bone abnormality
Xray/Bone lesion, solitary lytic
Xray/Bone lesions, multiple 'punched out'
Xray/Multiple lytic lesions of skull
Xray/Skull abnormality
Xray/Skull single lytic lesion
Associated Diseases & Rule outs
Rule Outs
Ewings sarcoma
Hypothalamic dysfunction
Osteogenic sarcoma
Osteomyelitis
Prolactinoma, pituitary
Associated Disease & Complications
Central diabetes insipidus
Diabetes insipidus
Exophthalmos
Gingival hyperplasia
Hand-Schuller-Christian disease
Hypothalamic lesion
Mastoiditis
Otitis externa, chronic
Otitis media
Panhypopituitarism
Mass in Bone
Disease Mechanism & Classification
Class
CLASS/Langerhan Cell/Tissue Macrophages involvement/disorder (ex)
CLASS/Pediatric disorders (ex)
CLASS/Hypothalamus/neurohypophysis involvement (ex)
CLASS/Gum/gingival involvement/disorder (ex)
Pathophysiology
Pathophysiology/Multisystem disease
Pathophysiology/Langerhans/histiocyte cell disease/LCD (ex)
Pathophysiology/Bone involvement/lesion
Pathophysiology/Immunoregulatory defect/causal
Process
PROCESS/Eponymic (category)
PROCESS/Inflammatory/Granulomatous disorder (category)
PROCESS/Metabolic/storage disorder (category)
PROCESS/Storage disorder (ex)
PROCESS/Proliferative/infiltrative disorder (ex)
PROCESS/Orbital inflammatory disease
Synonyms
Synonym
Chronic differentiated progressive histiocytosis, Chronic disseminated histiocytosis X, Chronic Histiocytosis X, Chronic idiopathic xanthomatosis, EOSINOPHILIC GRANULOMA MULTIFOCAL, Generalised histiocytosis of bones, Generalized histiocytosis of bones, Hand Schuller Christian disease, Hand Schueller Christian disease, Hand Schueller Christian Syndrome, Hand Schuller Christian, Hand Schüller Christian, Hand Schuller Christian diseas, Hand Schuller Christian disease, Hand Schüller Christian disease, Hand Schuller Christian disease (disorder), Hand Schüller Christian disease (disorder), Hand Schuller Christian disease (obs), Hand Schuller Christian syndr, Histiocytosis X (chronic), Histiocytosis X chronic, HISTIOCYTOSIS X II, Langerhans cell histiocytosis multifocal, Langerhans cell histiocytosis multifocal (morphologic abnormality), Langerhans cell histiocytosis poly ostotic, SCHUELLER CHRISTIAN DISEASE, Schuller Christian, Schüller Christian, Schuller Christian syndrome, Systemic reticuloendothelial granuloma, X histiocytosis chronic, Synonym/Christians disease, Synonym/Craniohypophyseal xanthoma syndrome, Synonym/Disseminated langerhans' histiocytosis, Synonym/Multifocal eosinophilic granuloma syndrome, Synonym/Schuller disease, Synonym/Xanthomatosis, chronic idiopathic
Definition
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External Links Related to Hand-Schuller-Christian syndrome
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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