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- Disease Information
- Disease Comparison
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Disease Processes ▼
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Disease Information for Haff disease/poisoning
- Clinical Manifestations
- Signs & Symptoms
- Akinetic rigid frozen Posture
- Chest Pain
- Chest pain, substernal/midline
- Non-Pleuritic Chest Pain
- Nausea
- Postprandial status
- Vomiting
- Dry mouth/Mucous membranes
- Bilateral Calf Pains
- Muscle Pain
- Muscle stiffness/rigidity
- Myalgias
- Pain in Extremities/Melalgias
- Tender or painful muscles/Myalgias
- Numbness/buttocks/thighs
- Numbness/distal fingers and toes
- Paresthesias
- Chest pain exacerbated on deep breathing
- Chest tightness/breathing response
- Bilateral flank/kidney pain
- Coca-Cola dark (coffee colored) urine
- Dark urine
- URINE Color Red
- Others/family same problems/epidemic/exposure
- Pain to light touch
- Total body pain/truncal/extremities
- Clinical Presentation & Variations
- Presentation/Fresh water fish Ingestion delay Rhabdomyolysis
- Disease Progression
- Course/Acute
- Course/Acute only
- Course/Lethal possible/not usual
- Course/Poisoning like onset/Abrupt severe
- Course/Prolonged/Protracted convalescence
- Course/Self limited usually
- Course/Slow curve fast break/over hours
- Onset/4-12 hours after exposure
- Prognosis/Full recovery usual
- Demographics & Risk Factors
- Exposure Factors
- Exposure/Clusters of cases in a short time
- Exposure/Ingestion Buffalo fish/Carp/Fresh water fish
- Exposure/Seabirds/Gulls reported deaths/kills
- Travel, Geographic & Climate Related Factors
- Residence/travel/Baltic/Sweden/Norway
- Residence/travel/Europe
- Residence/travel/Finland
- Residence/travel/Russia/Ukraine
- Ethnic or Racial Factors
- Ukrainian population
- Event, Activity, Behavioral & Seasonal Factors
- Event/Community clusters/family members also ill
- Event/Seasonal events/exacerbation
- Event/Summertime manifestations
- Laboratory Tests
- Abnormal Lab Findings (Non Measured)
- CPK Extreme levels/MB fraction < 5" (Lab)
- Transaminase elevation (Lab)
- Very High CPK
- URINE Color Brown
- Abnormal Lab Findings - Increased
- ALT (SGPT) (Alanine transferase) (Lab)
- Aspartamine aminotransferase (SGOT, AST) (Lab)
- AST (SGOT) (aspartamine transferase) (Lab)
- CPK/CK/Creatine kinase/Creatine phosphokinase (Lab)
- Lactic Dehydrogenase (LDH LH) (Lab)
- Myoglobin
- URINE Myoglobin
- Associated Diseases & Rule outs
- Associated Disease & Complications
- Acute Renal Failure
- Azotemia/Acute
- Fish poisoning
- Fish poisoning neuropathic syndrome
- Food poisoning
- Haff disease/poisoning
- Myoglobinemia
- Myoglobinuria
- Rhabdomyolysis
- Toxic Nephritis/Nephropathy
- Akinetic Rigid Syndrome
- Disease Mechanism & Classification
- Class
- CLASS/Reportable/CDC/National list infection (ex)
- CLASS/Muscle involvement/manifestations
- Process
- PROCESS/Eponymic (category)
- PROCESS/INCIDENCE/Acquired disorder
- PROCESS/INCIDENCE/Extremely rare disease
- PROCESS/INCIDENCE/Regional specific
- PROCESS/Poison/specific (category)
- Toxin
- TOXIN/ Delay/Slow curve fast break/hours
- TOXIN/CDC Reportable/Public health issue
- TOXIN/Food lethal to chickens/farm animal test
- TOXIN/Hexane extractable/heat stable poison/fish
- TOXIN/Latency after exposure/ingestion
- TOXIN/Poison/Zoologic/stings/bites (category)
- TOXIN/Toxin/heat stable (ex)
- Synonyms
- Synonym
- Haff disease poisoning, Synonym/Buffalo fish poisoning, Synonym/Haff disease
- Treatment
- Drug Therapy - Indication
- RX/Fluid/electrolytes intravenous
- RX/Hydration/fluids/IV
- RX/Mannitol (Osmotrol)
- Definition
-
Fish poisoning from fresh-water fish, burbot, carp-like species (buffalo fish, pike); delayed onset (within 24 hrs) but rhabdomyolysis with myoglobinuria and muscle pain; presents in seasonal community clusters seen in Baltic countries but also mississippi and california; lipid soluble heat stable specific poison (formerly thought to be from arsenic-not proven)
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- External Links Related to Haff disease/poisoning
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)
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