Disease Information for Gustatory sweating syndrome [Frey]

Clinical Manifestations
Signs & Symptoms
Gustatory sweating ear/temple/cheek
Associated Diseases & Rule outs
Associated Disease & Complications
Gustatory sweating syndrome
Disease Mechanism & Classification
CLASS/Neurologic (category)
CLASS/Peripheral nerve disease (ex)
Pathophysiology/Anatomically strategic lesion (ex)
PROCESS/Vegetative-Autonomic/Endocrine (category)
FREY SYNDROME, Gustatory Hyperhidroses, Gustatory Hyperhidrosis, Gustatory hyperhidrosis (disorder), Gustatory sweating, Gustatory sweating (finding), Hyperhidroses Gustatory, Hyperhidrosis Gustatory, Sweating Gustatory, Synonym/Auriculotemporal nerve syndrome, Synonym/Auriculotemporal syndrome, Synonym/Dupuy's syndrome, Synonym/Frey-Baillarger syndrome, Synonym/Frey's syndrome

Frey"s Syndrome

Auriculotemporal Syndrome

Baillarger"s Syndrome

Dupuy"s Syndrome

Salivosudoriparous Syndrome

Sweating Gustatory Syndrome

von Frey"s Syndrome

Disorder Subdivisions

General Discussion

Frey"s Syndrome is a rare neurological disorder that results from injury or surgery near the parotid glands (which manufacture saliva), damaging the facial nerve. The parotid glands are the largest salivary glands and are located on the side of the face below and in front of the ear. This syndrome is characterized by flushing or sweating on one side of the face when certain foods are consumed. The symptoms usually are mild and well tolerated by most individuals. Relief from symptoms may require treatment in some cases.

[NORD 2005]


Frey"s syndrome

Also known as:

Baillarger’s syndrome

Dupuy’s syndrome

Frey-Baillarger syndrome


Gustatory sweating, auriculo-temporal syndrome.

Associated persons:

Jules-Gabriel-François Baillarger

L. E. Dupuy

Lucja Frey-Gottesman


Syndrome characterized by warmth and sweating in the malar region of the face on eating or thinking or talking about food, brought on by eating foods that produce a strong salivary stimulus. It may follow damage in the parotid region by trauma, mumps, purulent infection or parotidectomy. It is thought that autonomous fibres to salivary glands have become connected in error with the sweat glands when they become reconnected after the damage which originally caused their connection to be interrupted. Flushing prevalent in females, sweating in males. It can persist for life. Some cases are congenital and probably due to birth trauma. The term "auriculotemporal syndrome" is misleading, as the skin innervated by the greater auricular nerve, the lesser occipital nerve, the long buccal nerve, or any cutaneous branch of the cervical plexus, may be involved.

The first description of a unilateral gustatory hyperhidrosis was done as early as in 1757 by the French surgeon M. Duphenix and in 1847 by Baillarger. Frey correlated the unusual physiologic phenomena (1923) and applied the descriptive term «auriculotemporal syndrome».

[whonamedit.com 2005]


External Links Related to Gustatory sweating syndrome [Frey]
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)