Disease Information for Gigantism, pituitary

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Clinical Manifestations
Signs & Symptoms
Prominent forehead/High forehead
Coarsening skin
Excess loose skin/child
Excess Sweating Children
Large Skin Pores
Oily Skin
Accelerated growth Child
Acromegalic habitus
Delayed adolescence/secondary sex changes
Increased spacing between teeth/sign
Large/protruding jaw/prognathism
Large hands/feet
Bitemporal hemianopsia
Arms too long for body
Increased Glove Size
Increased Shoe Size
Macrocephaly/Large head
Megalocephaly
Skull/head enlargement
Tall child
Coarsened facial features
Decreased exercise tolerance/effort fatigue
Increased Hat Size
Tall Adult
Disease Progression
Onset/Before puberty
Demographics & Risk Factors
Established Disease Population
Patient/Acromegaly
Family History
Family history/MEA/endocrine tumors
Laboratory Tests
Abnormal Lab Findings - Decreased
Thyroglobulin (Lab)
Abnormal Lab Findings - Increased
Creatinine, serum (Lab)
Growth hormone/STH, plasma (Lab)
Insulin level (Lab)
Phosphate Serum (Lab)
Somatomedin-C/Insulin-like Growth Factor/IGF-1 (Lab)
URINE 17-Ketosteroids
URINE Growth hormone
Diagnostic Test Results
Other Tests & Procedures
TEST/Abn growth hormone level /glucose suppression test
TEST/Glucose intolerance/GTT abnormal
Visual Fields Test Abnormal
Visual fields/Bitemporal visual field defects
Pathology
PATH/Visceromegaly
CT Scan
CT Scan/Head Brain Abnormality
CT Scan/Head Enlarged pituitary gland
MRI/Head Scan Abnormal
X-RAY
Xray/Cardiomegaly/Chest
Xray/Cortical thickening skull
Xray/Enlarged sella/Head
Xray/Enlarged sinuses/Head
Xray/Frontal bossing, infant/Skull
Xray/Jaw/mandible abnormality
Xray/Parietal bossing/Skull
Xray/Wide phalanges
Xray/Bilateral large kidneys/KUB
Ultrasound
Echo/Heart Multichamber enlargement
Associated Diseases & Rule outs
Associated Disease & Complications
Carpal tunnel syndrome
Diabetes mellitus
Gigantism
Hyperphosphatemia
Organomegaly
Osteoarthritis in Young Adults
Osteoarthritis, degenerative
Sellar tumor/suprasellar extension
Umbilibal Anomalies
Umbilical hernia
Disease Mechanism & Classification
Class
CLASS/Endocrine gland (category)
CLASS/Pituitary gland involvement/disorder (ex)
Pathophysiology
Pathophysiology/Enlarging pituitary gland
Pathophysiology/Hypersomatotropism
Pathophysiology/Inc phosphorous/tubular reabsorption
Process
PROCESS/Endocrine/humoral disorders (category)
PROCESS/Vegetative-Autonomic/Endocrine (category)
Synonyms
Synonym
Acromegaly and gigantism, Acromegaly and pituitary gigantism, Gigantism and acromegaly, Gigantism and acromegaly (disorder), Synonym/Launois' Syndrome
Treatment
Drug Therapy - Indication
RX/Bromocriptine (Parlodel)
RX/Octreotide (Sandostatin)
RX/Pasireotide (Somatostatin agonist) exp
Definition
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External Links Related to Gigantism, pituitary
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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