Disease Information for Gas gangrene

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Clinical Manifestations
Signs & Symptoms
Paroxysmal Shivering
Rigors/Shaking chills
Teeth Chattering
Uncontrollable Shaking
Low Blood Pressure
Signs of Poor Perfusion
Tachycardia/Fast heart rate
Bulla/bullous rash
Crepitus, subcutaneous
Sweating Excess Perspiration
Vesicobullous rashes
Muscle Pain
Muscles swelling
Myalgias
Tender or painful muscles/Myalgias
Chills
Fever
Fever Febrile Possible
Flu-Like Syndrome
Foul odor/lesion
Foul smelling infection
Gas in discharge/exudate
High body temperature
Clinical Presentation & Variations
Anemia with Low Reticulocyte Count
Disease Progression
Course/Acute
Course/Acute only
Course/Catastrophic presentation/onset
Course/Fulminant/Precipitous
Course/Potentially lethal/untreated
Lethal Potential
Demographics & Risk Factors
Sex & Age Groups
Population/Male
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Acute inflammatory markers elevated (Lab)
ALT (SGPT) over 120/2 1/2 X normal elevation (Lab)
Indirect bilirubin inc/normal direct bil. (Lab)
Normocytic Anemia/High Retic count
Normocytic anemia/low retic count
SGOT over 120 elevation/ 2 1/2 X normal (Lab)
Transaminase elevation (Lab)
Very High CPK
Abnormal Lab Findings - Increased
Aldolase, serum (Lab)
Aspartamine aminotransferase (SGOT, AST) (Lab)
AST (SGOT) (aspartamine transferase) (Lab)
Bilirubin, serum (Lab)
CK-MM (Lab)
CPK/CK/Creatine kinase/Creatine phosphokinase (Lab)
Indirect bilirubin (Lab)
Spherocytes (Lab)
URINE Hemoglobin
Diagnostic Test Results
X-RAY
Xray/Air/gas in muscle/tendon/bursal areas
Xray/Air/gas in soft tissues
Xray/Gas in tissues finding
Associated Diseases & Rule outs
Rule Outs
Cellulitis
Associated Disease & Complications
Bilirubinemia
Brisk Hemolysis/Active
Death Outcome
Emphysema, subcutaneous
Hemoglobinuria
Hemolysis anemia/acute/active
Hemolytic anemia of infection/acute
Hypotension
Infectious myopathy
Myoglobinuria
Myopathy
Rhabdomyolysis
Septic shock Pyogenic Endotoxic
Shock
Disease Mechanism & Classification
Specific Agent
AGENT/Anaerobes/unusual bacteria (category)
AGENT/Anaerobic bacteria (ex)
Class
CLASS/Muscle disorder (ex)
CLASS/Muscle/tendon/extremities (category)
Pathophysiology
Pathophysiology/Anaerobic infection setup
Pathophysiology/Hemolysis
Pathophysiology/Hemolytic process/effect
Process
PROCESS/Infection/agent specific (category)
Synonyms
Synonym
(Gas gangrene) or (Clostridium infection), Clostridial myonecrosis, CLOSTRIDIAL MYONECROSIS (GAS GANGRENE), CLOSTRIDIAL MYONECROSIS GAS GANGRENE, Clostridial myositis, Clostridial myositis as a result of gas gangrene, Clostridium gas forming, GANGRENE GAS, gangrene gas gangrene, Gangrenes Gas, Gas bacillus infection, Gas bacillus infection or gangrene, Gas gangrene, Gas gangrene (disorder), Gas gangrene due to Clostridia, Gas Gangrenes, Malignant edema, Malignant oedema, myonecrosis Clostridium, Progressive emphysematous necrosis, Synonym/Clostridial myonecrosis
Treatment
Drug Therapy - Indication
RX/Clindomycin (Cleocin) application
RX/Hyperbaric oxygen therapy
RX/Penicillin
SX/Debridement
Surgical Procedures or Treatments
SX/Surgery
SX/Surgical emergency
Other Treatments
TX/Rapid horse serum allergy desensitivation
Definition

A severe condition resulting from bacteria invading healthy muscle from adjacent traumatized muscle or soft tissue. The infection originates in a wound contaminated with bacteria of the genus CLOSTRIDIUM. C. perfringens accounts for the majority of cases (over eighty percent), while C. noyvi, C. septicum, and C. histolyticum cause most of the other cases.

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External Links Related to Gas gangrene
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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