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Disease Information for Fournier/Necrotizing fasciitis/genitals

Clinical Manifestations

Signs & Symptoms

Groin Pain

Pain in crotch/perineum

Low Blood Pressure

Signs of Poor Perfusion

Tachycardia/Fast heart rate

Bruising/Ecchymosis

Ecchymosis, massive, flank

Perineal/Crotch/Saddle area involvement/sign

Perineal/groin lesions

Eschar/ecchymosis scrotum/perineum/sign

Perineal pain/male

Scrotal edema/swelling

Scrotal lesions/ulcerative

Scrotal pain

Swelling of scrotum

Testicular pain

Unilateral Tender/Painful Testicle

Excessive/easy bruising tendency

Body wall ecchymosis/sign

Pain on defecation

Inguinal/groin adenopathy

Thigh/Leg Swelling Unilateral Severe

Perineal pain female

Perineal Mass

Suprapubic pain

Acutely ill patient/signs

Collapse/Prostration

Constitutional symptoms

Large local swollen/red/painful area sign

Perineal swelling/edema

Toxic and Febrile Septic

Disease Progression

Course/Acute

Course/Acute only

Course/Catastrophic presentation/onset

Course/Difficult Diagnosis

Course/Lethal

Course/Potentially lethal/untreated

Course/Slow curve/fast break over 24 hrs

Lethal Potential

Demographics & Risk Factors

Established Disease Population

Patient/Non-compliant

Patient/Poor personal hygiene

Patient/Diabetes mellitus

Population Group

Man

Sex & Age Groups

Population/Adult Aged Only

Population/Adult/all

Population/Male

Population/Male-only/limit

Population/Man patient

Laboratory Tests

Microbiology & Serology Findings

Microlab/Bacteroides isolation/culture

Microlab/Eschericia coli isolation/culture

Abnormal Lab Findings - Increased

Aldolase, serum (Lab)

Diagnostic Test Results

X-RAY

Xray/Air/gas in soft tissues

Associated Diseases & Rule outs

Rule Outs

Cellulitis

Decubitus ulcer/Bedsores

Tinea cruris

Associated Disease & Complications

Abscess, perianal/pararectal

Anaerobic bacterial infection

Bacteremia Septicemia

Constipation

Death Outcome

Fourniers/Necrotizing fasciitis/genitalia

Septic shock Pyogenic Endotoxic

Septicemic shock

Shock

Disease Synergy - Causes

Synergy/Poor personal hygiene

Disease Mechanism & Classification

Specific Agent

AGENT/Anaerobic bacteria (ex)

Class

CLASS/Dermatologic/Subcutaneous (category)

CLASS/Genital, male (category)

CLASS/Scrotum involvement/disorder (ex)

CLASS/Fascia involvement/disorder (ex)

Pathophysiology

Pathophysiology/Anaerobic infection setup

Pathophysiology/Polymicrobial infection process

Pathophysiology/Gangrene/skin/subcutaneous tissue

Pathophysiology/Subcutaneous manifestation/involvement

Process

PROCESS/Degenerative/necrosis disorder (category)

PROCESS/Necrosis (ex)

Synonyms

Synonym

Entire genital organ, Entire genital organ (body structure), Fasciitides Necrotizing, Fasciitis necrotising, FASCIITIS NECROTIZING, Fascitides Necrotizing, Fascitis Necrotizing, GANGRENE HEMOLYTIC STREPTOCOCCUS, Genital organ, Genital organ (body structure), Genital Organs, Genitalia, genitals, Necrotising cellulitis, Necrotising erysipelas, Necrotising fasciitis, Necrotising myositis, Necrotizing cellulitis, Necrotizing erysipelas, Necrotizing Fasciitides, Necrotizing fasciitis, Necrotizing fasciitis (disorder), Necrotizing Fascitides, Necrotizing Fascitis, Necrotizing myositis, Organ Genital, Organs Genital, Streptococcal gangrene, Synonym/Fournier's disease, Synonym/Meleney's gangrene/fasciitis

Treatment

Drug Therapy - Indication

RX/Amoxicillin-clavulanic acid (Augmentin)

RX/Ampicillin/sublactam (Unasyn)

RX/Antibiotic

RX/Hyperbaric oxygen therapy

SX/Debridement

Surgical Procedures or Treatments

SX/Surgery

SX/Surgery Incision/Drainage

SX/Surgical emergency

SX/Surgical resection/removal/biopsy

Other Treatments

TX/Medical/surgical emergency

Definition

Fournier Gangrene; Fournier Disease; Fournier Gangrene;

Necrotizing Fasciitis of the Perineum and Genitalia;

Synergistic Necrotizing Fasciitis of the Perineum and Genitalia; Fournier gangrene is a serious, rapidly progressive infective gangrene involving the scrotum, penis, and/or perineum caused by a broad array of microorganisms, acting in mutual support of one another (synergistically) and usually resulting from local trauma, operative procedures, or urinary tract disease; more frequently among male adults, has been identified also among women and children; Treatment usually consists of the surgical debridement of extensive areas of dead tissue (necrosis, necrotic) and the administration of broad-spectrum intravenous antibiotics Surgical reconstruction may follow where necessary---------- [NORD 2005]-------------

(Edit)

External Links Related to Fournier/Necrotizing fasciitis/genitals

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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