Disease Information for Fondaparinux (Arixtra) Administration/Toxicity

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Disease Mechanism & Classification
Drugs
DRUG/Anticoagulant medications (examples)
DRUG/Heparin analog (example)
DRUG/Heparin low molecular weigt derivative (example)
DRUG/Safe in pregnancy patient (B)
DRUG/Under FDA/study 2001
DRUG/Lowest active unit/five sugar heparin
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
administration, Fondaparinux (Arixtra), Brand name/Arixtra (Fondaparinux)
Treatment
Drug Dosage
DRUG/.$$$$ Very Expensive
DRUG/.$$$$$ Most Expensive
DRUG/2002 new drug (RX)
DRUG/Dose 2.5 mgm (Unit/Pill/Capsule size).
DRUG/Dose once daily (RX)
DRUG/Dose Unit dose Vial preparation
DRUG/Injectable medication (parenteral)
DRUG/Injectable preparation only
DRUG/Subcutaneous administration medication
-Renal excretion important pathway/drug
Definition

Anticoagulant injection;pentasaccharide selectively inhibits Factor Xa (activated) in coagulation cascade;used as low molecular weight heparin for DVT prophylaxis; Subcutaneous injection last 2 days;prolonged half life in renal patients; there is NO protamine rescue with this drug; pentasaccharide smallest moeity for heparin activity

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External Links Related to Fondaparinux (Arixtra) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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