Disease Information for Fluorouracil (5FU/Adrucil/Efudex) adm

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Clinical Manifestations
Signs & Symptoms
Baldness/Alopecia
Bluish/black pigmentation/nails
Hair loss
Non-scarring Alopecia/balding
Rash
Diarrhea
Oral mucosa white lesions
Staggering Gait
Unable to tandem walk/straight line
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Macrocytosis/smear (Lab)
Abnormal Lab Findings - Increased
FTI/Free Thyroxin Index (Lab)
Platelet count (Lab)
Thyroid Binding Globulin (Lab)
Thyroxin/T4 (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Acute gastroenteritis
Agranulocytosis
Angina pectoris
Angina, spasm type
Bone marrow failure/exhaustion
Chemical/toxic stomatitis
Drug induced Baldness/Alopecia
Drug induced Diarrhea.
Drug induced Myelosuppression.
Drug induced Photosensitivity rash
Drug induced Thrombocytopenia.
Drug rash/Drug induced rash
Granulocytopenia/Neutropenia
Hand-foot dermatitis/chemo syndrome
Myelosuppression
Photosensitivity dermatitis
Phototoxicity
Thrombocytopenia
Thrombocytosis
Ataxia Disorder
Disease Mechanism & Classification
Drugs
DRUG/Anti-tumor antimetabolite (example)
DRUG/Breast milk secretion/Danger
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/ELF ChemoRX protocol (comb)
DRUG/Pyrimidine antagonists (example)
DRUG/Specialized usage (example)
DRUG/Teratogenic potential/effect (D plus )
DRUG/Topical medication (example)
DRUG-Liver metabolism/bile excretion
DRUG/Topical chemotherapetic medication (ex)
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
2,4 Dioxo 5 fluoropyrimidine, 2,4(1H,3H) Pyrimidinedione 5 fluoro, 5 Fluoro 2,4(1H 3H) pyrimidinedione, 5 Fluoro 2,4(1H,3H) pyrimidinedione, 5 Fluorouracil, 5 Fluracil, 5 Fu, 5fluorouracil, 5Fluracil, 5FU, 5FU Fluorouracil, Fluoro Uracil, Fluorouracil, Fluorouracil (product), Fluorouracil (substance), FLUOROURACIL PREPARATION, Fluoruracil, Fluouracil, FU, Brand name/5FU (Fluorouracil), Brand name/Adrucil (Fluorouracil), Brand name/Efudex (Fluorouracil), Brand name/Fluoroplex (Fluorouracil)
Treatment
Drug Therapy - Indication
RX/Chemo Saltz Regimen Protocol
RX/IFL Chemotherapy protocol
Drug Dosage
DRUG/.$$$$ Very Expensive
DRUG/.$$$$$ Most Expensive
DRUG/Dose special schedule/course
DRUG/Intravenous administraton RX
Definition

Cancer chemotherapy drug; Antimetabolite class usually substituted purine or pyrimidine bases interfere with DNA synthesis.

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External Links Related to Fluorouracil (5FU/Adrucil/Efudex) adm
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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