Disease Information for Flecainide (Tambocor) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Dizzy on Standing/Giddy Response
Hypotension with Relative Bradycardia
Low Blood Pressure
Orthostatic drop in blood pressure
Slow pulse/Bradycardia
Diagnostic Test Results
EKG (ECG)
EKG/Prolonged PR Interval (ECG)
EKG/Widened QRS pattern (ECG)
EKG/AV Nodal Block/Complete
EKG/Changes/abnormalities (ECG)
Associated Diseases & Rule outs
Rule Outs
Digitalis toxicity/poisoning
Associated Disease & Complications
Bradyarrhythmias
Cardiac arrhythmias
Cardiac conduction defects
Drug induced Arrhythmias
Heart block, complete
Hypotension
Orthostatic syncope Hypotension
Torsades de pointes/ventricular tachycardia
Disease Mechanism & Classification
Drugs
DRUG/Anti-arrhythmic medication (example)
DRUG/Cardiovascular meds (examples)
DRUG/Chronic pain/Neuropathic pain adjunct medication
DRUG/Class I antiarrhythmic drug (example)
DRUG/Class IC antiarrhythmic agent (example)
DRUG/Class one/sodium channel myocardial blocker (example)
DRUG/metabolized by CYP 3A pathway
DRUG/Proarrhythmic drug effect (example)
DRUG/Sodium-channel block effect/toxicity
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin
TOXIN/Hypotension relative bradycardia
Synonyms
Synonym
Benzamide N (2 piperidinylmethyl) 2,5 bis(2,2,2 trifluoroethoxy), Flecainide, Flecainide (product), Flecainide (substance), FLECAINIDE PREPARATION, Brand name/Tambocor (Flecainide)TOXIC
Treatment
Drug Dosage
DRUG/Drug discontinued/TOXIC (RX)
Definition

Anti-arrhythmic medication;Von Williams class I-C;

caused torsade de points ventricular tachycardia

and ventricular arrhythmias/deaths on CAST trials; withdrawn as toxic drug;Can be used for non-sustained

ventricular tachycardia in normal hearts.

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External Links Related to Flecainide (Tambocor) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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