Disease Information for Fibromyositis/Fibromyalgia syndrome

Synonyms:

Diffuse myofascial pain synd, Diffuse myofascial pain syndrome, Fibromyalgia, Fibromyalgia Fibromyositis Syndrome, Fibromyalgia Fibromyositis Syndromes, Fibromyalgia RETIRED, Fibromyalgia Syndrome, Fibromyalgias, FIBROMYOSITIS, Fibromyositis (disorder), Fibromyositis Fibromyalgia Syndrome, Fibromyositis Fibromyalgia Syndromes, Fibrositides, fibrositis, Fibrositis (disorder), Fibrositis unspecified, Fibrositis unspecified (disorder), MPD syndrome, MPDS Myofacial pain dysfunction syndrome, MPDS Myofac pain dysfunct syn, Muscular Rheumatism, Muscular rheumatism (disorder), Myofac pain dysfunct syndrome, Myofacial pain dysfunction syndrome, Myofascial pain dysfunct syn, Myofascial pain dysfunction syndrome, Myofascial pain syndrome, Myofascial Pain Syndrome Diffuse, Rheumatism Muscular, RHEUMATISM TENSION, Syndrome Fibromyalgia Fibromyositis, Syndrome Fibromyositis Fibromyalgia, Syndromes Fibromyalgia Fibromyositis, Syndromes Fibromyositis Fibromyalgia

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Definition:

Chronic fatigue with fibromyalgia syndromeincludes some cognitive and myalgia trigger points; unknown cause likely post- infection poorly understood process with few physical

or lab finding; Exercise helps long term care but often pripitates relapse if too vigorous; lyme disease; post-polio syndrome; major stres events often a trigger; suspected microbes considered now Herpetic or Human lymphotrophic virus (HLTV-2, HHV-6); Lack of REM sleep level four;there is intrusion of alpha waves into delta-wave sleep on EEG; sensitive to nor-epinephrine epinephrine which causes increased pain; low growth hormone, somatomedin-a, melatonin, endorphines, altered serotonin;chlorpromazine and gamma hydroxybutyrate help

with more REM sleep; Substance P increased CSF and cytokine effectors peripheral serum/mononuclear cells increased IL-6 amd IL-8 cytokines; high TNF in some--------------------

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