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Disease Information for Exenatide (Byetta) Administration/Toxicity injection

Diagnostic Test Results

Isotope Scan

Isotope/Gastric Emptying Delay

X-RAY With contrast

UGI/Gastric Emptying Time Delay

Associated Diseases & Rule outs

Associated Disease & Complications

Hypoglycemia, diabetic/treatment

Disease Mechanism & Classification

Drugs

DRUG/Anti-diabetic medication (example)

DRUG/Dipeptidyl peptidase-4 (DPP-4) inhibitor

DRUG/Dose before meals

DRUG/Glucagon Like Peptide GLP-1 Analog

DRUG/Incretin like anti-glycemic

DRUG/Novel drug/Class

DRUG/Novel anti-diabetic Incretin mimic/Amylin effect

Pathophysiology

Pathophysiology/Delayed gastric emptying/gastrostasis

Synonyms

Synonym

Exenatide (Byetta) Administration injection, Brand Name/Bydureon (Exenatide) XR, Brand name/Byetta (Exenatide) GIP/GLP-1 Analog

Treatment

Drug Dosage

DRUG/2005 New Release

DRUG/Dose BID Medication

DRUG/Injectable medication (parenteral)

DRUG/Injectable preparation only

DRUG/Orally ineffective drug

DRUG/Subcutaneous administration medication

Definition

Exenide generic [Byetta} is an increatin mimetic injection pen with 5 mcg or 10 mcg delived dose; adjunctive therapy for glycemic control; sensitizes the beta cells to glycemic response acting like glucagon-like-peptide-1 [GLP-1]; Exenatide moderates glucagon levels and slows gastric emtying; generally used in metformin and/or sulfonourea treated type II diabetyics before long term insulin started; dose of sulfonoureas should be lowered; given as injection BID; Metformin dose stays the same;

60 minutes before breakfast and supper; In general reduces insulin demand by moderating swings in glucose levels usually reducing hepatic release;

----------------------------[Byetta_com website 2006]-------

BYETTA (bye-A-tuh) is the first in a class of medicines for type 2 diabetes called incretin mimetics; BYETTA improves blood sugar control in adults with type 2 diabetes and is used with pills like Glucophage® (metformin), and/or a sulfonylurea like Amaryl® (glimepiride), Glucotrol® (glipizide), Micronase® (glyburide), and others; ------------------[byetta_com amylin website 2006]---------

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External Links Related to Exenatide (Byetta) Administration/Toxicity injection

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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