Disease Information for Estramustine (Emcyt) Administration/Toxicity

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Associated Diseases & Rule outs
Associated Disease & Complications
Fetal anomaly
Disease Mechanism & Classification
Drugs
DRUG/Alkylating agents (example)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Teratogenic potential/effect (D plus )
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
17beta (estra 1,3,5(10) triene 3,17 diol 3 (bis(2 chloroethyl)carbamate), EM, Estra 1,3,5(10) triene 3,17 diol (17beta) 3 (bis(2 chloroethyl)carbamate), estra 1,3,5(10)triene 317beta diol 3 (N,N bis (2 chloroethyl)carbamate), Estradiol 3 (bis(2 chloroethyl)carbamate), estradiol 3 bis(2 chloroethyl)carbamate, Estramustine, Estramustine (product), Estramustine (substance), ESTRAMUSTINE PREPARATION, RO 21 8837, Brand name/Emcyt (Estramustine), Brand name/Estracyt (Estramustine)
Definition

Primarily an Antineoplastic cancer chemotherapy drug. Alkylating agents interferes with methylation of DNA in mitosis, inhibits cell division. Speciality use only is recommended; a dangerous class of drugs with predictable bone marrow suppression often. Nitrogen mustard class

often more powerful.

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External Links Related to Estramustine (Emcyt) Administration/Toxicity
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Merck
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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