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Disease Information for Erythroderma desquamativatum, infants

Clinical Manifestations

Signs & Symptoms

Scaling/Skin finding

Neonatal edema/anasarca

Demographics & Risk Factors

Population Group

Child

Infant

Population/Pediatrics population

Sex & Age Groups

Population/Child

Population/Child-Infant Only

Population/Children/all

Population/Infant

Associated Diseases & Rule outs

Associated Disease & Complications

Erythroderma desquamativatum, infants

Neonatal Erythroderma

Disease Mechanism & Classification

Class

CLASS/Pediatric disorders (ex)

CLASS/Dermatologic/Subcutaneous (category)

CLASS/Skin disorder (ex)

Process

PROCESS/Reference organ/system (category)

Synonyms

Synonym

Erythroderma desquamativatum infants, Synonym/Leiner's disease

Definition

Leiner"s disease; Leiner’s syndrome; Erythrodermia desquamativa Leiner; Leiner-Moussous disease; Dermatitis exfoliativa generalisata; desquamative erythrodermia in infants; eczema universale seborrheicum; erythrodermia desquamativa in infants; erythroderma desquamativum; erythrodermic seborrhoic dermatitis in the trianon of life; érythrodermie desquamative des nourrisons (French); exfoliative dermatitis; seborrhoic diathesis in infants;

Syndrome characterised by desquamation (severe generalised seborrhoeic dermatitis), recurrent local and systemic infection, severe diarrhoea, marked wasting and central nervous system deficiency, and failure to thrive; It begins as seborrhoic eczematoid lesions of the scalp and face or the gluteal region, eventually spreading to other areas; Keratitis and corneal ulcers may occur; Due to complement C5 deficiency in infancy; Prevalent in infant females; rapid onset in 2nd to 4th month of life; Breast-fed infants are most frequently affected-------[whonamedit_com 2005]----------------------------------------------------------------

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External Links Related to Erythroderma desquamativatum, infants

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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