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Disease Information for Erythema marginatum

Clinical Manifestations

Signs & Symptoms

Annular erythema lesion, large

Annular lesions rash

Fever and Rash

Mucocutaneous Lesions

Mucocutaneous rash/signs

Non-pruritic rash

Rash

Rash with well demarcated lesions

Fever

High body temperature

Demographics & Risk Factors

Established Disease Population

Patient/Rheumatic fever

Associated Diseases & Rule outs

Rule Outs

Chronic hives/urticaria

Tinea corporis

Urticaria/hives

Associated Disease & Complications

Erythema marginatum

Disease Mechanism & Classification

Class

CLASS/Dermatologic/Subcutaneous (category)

Pathophysiology

Pathophysiology/Shared Antigens Strep A Human Tissue

Process

PROCESS/Allergy/collagen/autoimmune (category)

Definition

Erythema marginatum;Erythema Marginatum: an evanescent, erythematous rash characteristically (though not commonly) seen in the early stages of rheumatic fever; The rash is not limited to rheumatic fever, however, and has also been reported in patients with allergic drug reactions, sepsis and glomerulonephritis; Although the rash is not pathognomonic of rheumatic fever, its presence is helpful in conjunction with other manifestations of rheumatic fever, particularly carditis with which it is most often associated; The rash is characterized by pink, evanescent, slightly raised small macules with a sharply demarcated and irregular border; The erythematous areas often have pale centers; The rash commonly occurs over the trunk and inner aspects of the upper arms and thighs, but never on the face; It is non-painful and rarely pruritic, may appear and disappear in a matter of hours only to return, and may be brought out by a hot bath or shower; The rash blanches on pressure, and is a transient rash which tends to migrate from place to place--[Jones criteria (revised)/Circulation 32:664, 1965]----------

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External Links Related to Erythema marginatum

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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