Disease Information for Ergotamine (Ergotrate/Cafergot) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Regional pallor/vasospasm
Vasospasm of extremities/Signs
Nausea
Vomiting
Acroparesthesias Acral Paresthesias
Toe pains
Dysesthesias
Paresthesias
Clinical Presentation & Variations
Presentation/Angina worse
Associated Diseases & Rule outs
Associated Disease & Complications
Angina pectoris
Angina, spasm type
Angina, unstable/crescendo/intermediate syndrome
Coronary ischemia
Drug induced Angina/Coronary vasospasm
Drug induced Pleural effusion
Drug induced Stroke/Cerebral ischemia/Bleed
Ischemia, cardiac
Ischemic bowel disease
Myocardial infarction, acute
Pericardial effusion
Precipitous labor
Raynaud's syndrome
Secondary Psychosis/Symptomatic
Non-Occlusive Bowel Infarction
Disease Mechanism & Classification
Drugs
DRUG/Anti-migraine medication (example)
DRUG/metabolized by CYP 3A pathway
Pathophysiology
Pathophysiology/Myocardial Ischemia Non-Arteriosclerosis
Pathophysiology/Mesenteric Ischemia Non-Occlusive
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin
TOXIN/NOT Diagnosed on USUALToxic screens
Synonyms
Synonym
Ergotaman 3',6',18 trione 12' hydroxy 2' methyl 5' (phenylmethyl) (5'alpha), Ergotamine, Ergotamine (product), Ergotamine (substance), ERGOTAMINE PREPARATION, Ergotamine product, Ergotamine product (product), Ergotamine product (substance), Brand name/Cafergot (Ergotamine-Caffeine), Brand name/Ercaf (Ergotamine-Caffeine), Brand name/Ergostat (Ergotamine), Brand name/Wigraine (Ergotamine-Caffeine)
Treatment
Drug Dosage
DRUG/Dose Given for specific effect
DRUG/Dose must be titrated to effect
DRUG/Dose Rectal enema/suppository available
DRUG/Dose single dose medication
DRUG/Oral medication (ex)
Definition

Ergot alkaloid synthetic drug;used in postpartum hemorrhage and uterine atony;oral and rectal and parenteral preparation; also used in acute migraine in combination with caffeine

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External Links Related to Ergotamine (Ergotrate/Cafergot) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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