Disease Information for Epilepsy, grand mal

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Clinical Manifestations
Signs & Symptoms
Abnormal movements/involuntary
Attacks, neurologic, recurrent, varied
Aura prodrome
CNS symptoms/signs
Myoclonus/Myoclonic jerks on exam
Seizures
Seizures/Children/recurrent
Sleeps off the event
Transient limb paralysis/palsy
Collapse/Prostration
Episodic symptoms/events
Fever
Near death experience/infant/SIDS survivor
Clinical Presentation & Variations
Presentation/High Temperature No Infection
Disease Progression
Course/Acute
Course/Attacks Episodic Spells
Course/Chronic disease crisis/flare/attacks
Course/Chronic disorder
Course/Paroxysmal
Course/Periodic Episodic
Course/Recurrent
Course/Recurrent illness pattern
Course/Relapsing
Onset/Abrupt/Sudden
Demographics & Risk Factors
Established Disease Population
Patient/Epilepsy
Population Group
Young Adult
Sex & Age Groups
Population/Adult Aged Only
Population/Adult/all
Population/Young adult
Diagnostic Test Results
Electrodiagnosis
EEG/Abnormality
EEG/Characteristic pattern abnormal
EEG/Period Sharp Wave complexes
EEG/Photic Driving Abnormal
EEG/Seizure activity abnormality
Associated Diseases & Rule outs
Associated Disease & Complications
Apnea
Convulsions (grand mal)
Epilepsy, grand mal
Epilepsy, psychomotor
Lactic acidosis
Lung abscess
Migraine headache syndrome
Petit mal seizure disorder
Pneumonia, aspiration
Seizure disorder (epilepsy)
Syncope/Fainting
Todds paralysis/postictal
Disease Synergy - Causes
Synergy/Sleep deprivation
Disease Mechanism & Classification
Class
CLASS/Brain/CNS disorder (ex)
CLASS/Neurologic (category)
Pathophysiology
Pathophysiology/Gene Locus Identified/OMIM database
Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
Pathophysiology/Hereditary disease/Adult manifestations
Pathophysiology/Epileptiform/epileptic disorder
Pathophysiology/Gene locus 8q25
Pathophysiology/Gene locus chromosome 8
Process
PROCESS/Vegetative-Autonomic/Endocrine (category)
Treatment
Drug Therapy - Contraindication
RX/Bupropion (Wellbutrin/Zyban)
Drug Therapy - Indication
RX/Anticonvulsants
RX/Carbamazepine (Tegretol)
RX/Phenobarbital
RX/Phenytoin
RX/Primidone (Mysoline)
RX/Valproic/divalproex (Depakote/Epival)
Other Treatments
TX/Ketogenic diet
Definition

A generalized seizure disorder characterized by recurrent major motor seizures; The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities; The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting; This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours; The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process)-------(From Adams et al, Principles of Neurology, 6th ed, p329)---------

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External Links Related to Epilepsy, grand mal
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Wikipedia
Merck
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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