Disease Information for Epidermolysis bullosa acquisita

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Clinical Manifestations
Signs & Symptoms
Blisters
Bulla/bullous rash
Bulla/normal base/no erythema
Cutaneous manifestations
Extensor surfaces/skin manifestations
Local lesion/skin rash
Nikolskys sign
Rash/Lesions occur on pressure points/Acral lesions
Residual Scars lower extremity lesions
Scarring/blistered skin areas
Skin fragile/thin/easily torn
Skin lesions
Skin sloughing/denuded/raw/oozing areas
Skin tears/easy abrasions signs
Skin trauma sensitive
Skin trauma/triggers bulla
Subepidermal Blisters
Thin skin/parchment-like skin
Vesicobullous rash in Elderly
Vesicobullous rash/lesions in Children
Vesicobullous rashes
Knee manifestation/involvement/secondary
Disease Progression
Course/Benign course/disorder
Course/Chronic disorder
Course/Chronic only
Demographics & Risk Factors
Population Group
Aged Adult
Middle Age Adult
Sex & Age Groups
Population/Adult Aged Only
Population/Adult/all
Population/Elderly Aged
Population/Fifties adult
Population/Middle-aged adult
Population/Seventies Adult
Laboratory Tests
Abnormal Lab Findings - Increased
Anti-basement membrane (BMZ/EBA/Collagen iv) skin
Diagnostic Test Results
Pathology
BX/Skin biopsy/Abnormal
BX/Skin biopsy/Blister subepidermal zone
BX/Skin biopsy/Subepidermal bulla/IGG complement/BMZ
Associated Diseases & Rule outs
Rule Outs
Pemphigoid, bullous
Pemphigus
Associated Disease & Complications
Epidermolysis bullosa
Epidermolysis bullosa acquisita
Milia
Disease Mechanism & Classification
Class
CLASS/Dermatologic/Subcutaneous (category)
CLASS/Skin disorder (ex)
Pathophysiology
Pathophysiology/Autoimmune skin/Sub-basal lamina/IGG
Process
PROCESS/Allergy/collagen/autoimmune (category)
PROCESS/Autoimmune disorder (ex)
PROCESS/INCIDENCE/Acquired disorder
PROCESS/Necrosis (ex)
Synonyms
Synonym
Acquired epidermolysis bullosa, Acquired epidermolysis bullosa (disorder), EBA Epidermoly bull acquisit, EBA Epidermolysis bullosa acquisita, Epidermolysis bull acquisita, Epidermolysis bullosa acquired, Epidermolysis Bullosa Acquisita, Synonym/Dystrophic epidermolysis bullosa
Treatment
Surgical Procedures or Treatments
SX/Biopsy
Definition

Form of epidermolysis bullosa characterized by trauma-induced, subepidermal blistering with no family history of the disease. Direct immunofluorescence shows IMMUNOGLOBULIN G deposited at the dermo-epidermal junction.

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External Links Related to Epidermolysis bullosa acquisita
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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