Disease Information for Eosinophilic Pneumonia prolonged/Chronic

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Clinical Manifestations
Signs & Symptoms
Night sweats
Sweating Excess Perspiration
Asymmetrical breathing
Bronchial breath sounds
Bronchospasm signs
Consolidation left base/signs
Consolidation right base/on exam
Cough
Cough Chronic
Cough Dry Non-productive
Dullness to percussion lung base
Dyspnea
Dyspnea at rest
Dyspnea on exertion
Dyspnea, chronic progressive
Localized decreased breath sounds
Localized dullness to percussion
Lung signs/abnormality
Rales
Rapid Breathing
Shortness of breath/SOB
Signs of consolidation/chest
Tachypnea/Increased respiratory rate
Unilateral Rales
Wheezing
Whispered pectroliloquy/egophony
Acutely ill patient/signs
Chills
Fever
Fever Febrile Possible
Flu-Like Syndrome
High body temperature
Malaise
Weight Loss
Clinical Presentation & Variations
Presentation/Wheeze Cough Dyspnea Adult
Disease Progression
Course/Chronic disorder
Course/Subacute
Demographics & Risk Factors
Exposure Factors
Exposure/Micropolyspora faeni Antigen/Allergy
Exposure/Thermoactinomyces antigen/allergy
Sex & Age Groups
Population/Female
Laboratory Tests
Microbiology & Serology Findings
Microlab/Sputum/Eosinophiles on smear
Abnormal Lab Findings (Non Measured)
Acute inflammatory markers elevated (Lab)
Extreme eosinophilia (Lab)
Abnormal Lab Findings - Increased
Eosinophiles (LAB)
Diagnostic Test Results
Other Tests & Procedures
Bronchopulmonary alveolar lavage/BAL/Abnormal
PFT/Abnormal pulmonary function tests
PFT/Carbon monoxide diffusion (DLCO)/Abnormal
PFT/Diffusion defect
PFT/DLCO (CO diffusion) Decreased
Pathology
PATH/Eosinophilic infiltrate/tissue
X-RAY
Xray/Chest abnormal
Xray/Bilateral pulmonary infiltrates/Chest
Xray/Chest/Lung fields/Abnormal
Xray/Dense infiltrates subpleural/not BP segmented/Chest
Xray/Infiltrate, pulmonary/Chest
Xray/Interstitial infiltrate/fibrosis/Chest
Xray/Lung consolidation/Chest
Xray/Peripheral/Inverse pulmonary edema pattern/Chest
Xray/Pulmonary infiltrate eosinophilia (PIE/Loeffler's syndrome)
Xray/Pulmonary Lesions/Lung
Xray/Transient pulmonary infiltrates/Chest
Associated Diseases & Rule outs
Rule Outs
Ascariasis, pulmonary larval infestation
Aspergillosis, invasive pulmonary type
Asthma
Bronchiolitis obliterans
Pneumonia, viral
Pneumonia/Bronchopneumonia
Associated Disease & Complications
Aspergillosis, mycetoma type, pulmonary
Asthma
Bronchiolitis obliterans
Bronchiolitis obliterans/organizing pneumonia/BOOP
Eosinophilia Hypereosinophilia
Eosinophilic pneumonia/prolonged
Hypereosinophilic syndrome
Pneumonia, recurrent
Pneumonia/Bronchopneumonia
Pneumothorax
Disease Mechanism & Classification
Class
CLASS/Lung Disorder (ex)
CLASS/Pulmonic (category)
Pathophysiology
Pathophysiology/Alveolar consolidation
Pathophysiology/Bronchospasm
Pathophysiology/Chronic intrinsic restrictive lung
Pathophysiology/Inflammatory lung disorder (ex)
Pathophysiology/Non-infectious alveolar consolidation
Process
PROCESS/Allergy/collagen/autoimmune (category)
PROCESS/Eosinophilic syndromes (ex)
PROCESS/Infected organ/abscess (category)
PROCESS/Inflammatory/Allergy/immune (ex)
Synonyms
Synonym
Eosinophilic pneumonia, Eosinophilic Pneumonias, EP Eosinophilic pneumonia, Pneumonia Eosinophilic, Pneumonias Eosinophilic, Synonym/Eosinophilia, pulmonary, prolonged, Synonym/Eosinophilosis, pulmonary, Synonym/Pulmonary infiltration eosinophilia
Treatment
Drug Therapy - Indication
RX/Corticosteroid (Cortisone)
Definition

diseases of known or unknown etiology characterized by eosinophilic pulmonary infiltrates and, commonly, peripheral blood eosinophilia; Eosinophilic pneumonia is sometimes called the pulmonary infiltrates with eosinophilia (PIE) syndrome; Causes include parasites (eg, roundworms, Toxocara larvae, filariae), drugs (eg, penicillin, aminosalicylic acid, hydralazine, nitrofurantoin, chlorpropamide, sulfonamides), chemical sensitizers (eg, nickel carbonyl inhaled as a vapor), and fungi (eg, Aspergillus fumigatus, which causes allergic bronchopulmonary aspergillosis; Most eosinophilic pneumonias, however, are of unknown etiology, although a hypersensitivity mechanism is suspected; Eosinophilia suggests a type I hypersensitivity reaction; other features of the syndrome (vasculitis, round cell infiltrates) suggest type III and possibly type IV reactions;

Eosinophilic pneumonias are often associated with bronchial asthma; Those associated with asthma and those of unknown etiology can be classified into three general groups: extrinsic bronchial asthma with the PIE syndrome, which often is allergic bronchopulmonary aspergillosis; intrinsic bronchial asthma with the PIE syndrome (chronic eosinophilic pneumonia), commonly with characteristic peripheral infiltrates on chest x-ray; and allergic granulomatosis (Churg-Strauss syndrome), a variant of polyarteritis nodosa with a predilection for the lungs; [Acute]Simple eosinophilic pneumonia (Löffler"s syndrome) may occasionally be associated with mild asthma; Eosinophilic pneumonias not associated with asthma include acute eosinophilic pneumonia, the eosinophilia-myalgia syndrome, and the hypereosinophilic syndrome; Acute eosinophilic pneumonia, a distinct entity of unknown cause, results in acute fever, severe hypoxemia, diffuse pulmonary infiltrates, and > 25% eosinophils in bronchoalveolar lavage fluid; it resolves promptly and completely with corticosteroid therapy; The eosinophilia-myalgia syndrome is associated with ingestion of large doses of contaminated L-tryptophan used as a dietary supplement; Pulmonary infiltrates occasionally occur along with the expected features of myalgia, muscle weakness, skin rash, and soft tissue induration resembling scleroderma; Diagnostic criteria for the hypereosinophilic syndrome are persistent eosinophilia > 1500 eosinophils/mm3 for more than 6 mo, lack of evidence for other known causes of eosinophilia, and systemic involvement of the heart, liver, spleen, CNS, or lungs;

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External Links Related to Eosinophilic Pneumonia prolonged/Chronic
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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