Disease Information for Dutasteride (Avodart) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Breast Swelling Bilateral
Impotence, relative
Loss of libido,male
Sexual dysfunction
Decreased taste ability/Hypoguesia
Loss of Taste
Loss of libido,women
Loss of pleasure/anhedonia/sex or food
Laboratory Tests
Abnormal Lab Findings - Decreased
Prostate Specific Antigen/PSA (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Drug induced Impotence.
Gynecomastia
Impotence/Erectile dysfunction disorder
Disease Mechanism & Classification
Drugs
DRUG/Inhibits DHT prostate (ex)
DRUG/Teratogenic/OBGYN Class X/Pregnancy DANGER
DRUG/Testosterone reductase inhibitor(5-alpha) effect
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
Dutasteride (Avodart) administration, Brand name/Avodart (Dutasteride)
Treatment
Drug Dosage
DRUG/.$$$ Expensive medication
DRUG/2002 new drug (RX)
DRUG/Dose 0.5 mgm (Unit/Pill/Capsule size)
DRUG/Dose once daily (RX)
DRUG/Injection Preparation NOT available
DRUG/Oral medication (ex)
Definition

a type I and II 5-alpha tetosterone reductase medication for BPH; oral preparation; highly teratogenic (no blood donation); can cause impotence, ejaculation problems, and gynecomastia

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External Links Related to Dutasteride (Avodart) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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