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Disease Information for Drug induced Hepatitis.

Clinical Manifestations
Signs & Symptoms: Yellow skin discoloration
: Anorexia Decreased appetite; Anorexia in Children; Anorexia in Elderly; Epigastric Pain
: Choluria/Biliuria in Children; Choluria/Biliuria in Elderly; Choluria/Biluria/Bilirubin urine; Fever with Jaundice; Jaundice, recurrent; Jaundice/Yellow skin and eyes; Tender liver/liver pain; Yellow eyeballs/Scleral icterus
: Delirium; Delirium/Agitated delirium; Fatigability
: Dark urine
: Chronic Fatigue; Constitutional symptoms; Fatigue; Fatigue Tiredness Exhaustion; Fever; Fever Febrile Possible; Flu-Like Syndrome; High body temperature; Malaise
Disease Progression: Course/Acute; Course/Chronic disorder
Demographics & Risk Factors
Established Disease Population: Patient/Cytotoxic drug treatment; Patient/On Medications long term/ usually
: Patient/Viral hepatitis
Laboratory Tests
Abnormal Lab Findings (Non Measured): Acute inflammatory markers elevated (Lab); ALT (SGPT) over 120/2 1/2 X normal elevation (Lab); AST/SGOT above 1000 units/very high; Hepatic Enzymes Abnormal (Lab); Liver Functions Abnormal (Lab); SGOT over 120 elevation/ 2 1/2 X normal (Lab); Transaminase elevation (Lab); Transaminase Levels Extreme
: URINE Color Brown
Abnormal Lab Findings - Decreased: BUN/Blood urea nitrogen (Lab)
Abnormal Lab Findings - Increased: Alkaline phosphatase, serum (Lab); ALT (SGPT) (Alanine transferase) (Lab); Aspartamine aminotransferase (SGOT, AST) (Lab); AST (SGOT) (aspartamine transferase) (Lab); Bilirubin, serum (Lab); Gammaglutamyl transferase/GGT (Lab); Indirect bilirubin (Lab); Iron, serum (Lab); Lactic Dehydrogenase (LDH LH) (Lab); LAP/Leucine Amino Peptidase (Lab); Nucleotidase/5 (Lab)
: URINE Bilirubin; URINE Urobilinogen
Diagnostic Test Results
Pathology: BX/Liver biopsy/Abnormal; BX/Liver biopsy/Fatty change in liver tissue; BX/Liver biopsy/Granulomas in liver; BX/Liver biopsy/Hepatocyte necrosis; BX/Liver Microvesicular fatty subcellular organelles
Associated Diseases & Rule outs
Rule Outs: Autoimmune hepatitis; Cholecystitis, acute; Fibromyositis/fibromyalgia syndrome; Hepatitis Delta Viral; Hepatitis E virus; Hepatitis, type A; Hepatitis, type B viral; Hepatitis, type C viral; Hepatitis, viral; Non-alcoholic fatty liver disease; Steatosis/Non-alcoholic steatosis hepatitis/NASH
: Chronic Hepatitis
Associated Disease & Complications: Acute Tubular Necrosis; Bilirubinemia; Cholestasis/intrahepatic biliary obstruction; Cholestatic Jaundice Syndrome; Chronic hepatitis/Active; Fatty liver; Granulomatous liver/hepatitis syndrome; Hepatitis, secondary; Obstructive jaundice syndrome; Toxic hepatitis
: Chronic Hepatitis
Disease Synergy - Causes: Synergy/Chronic alcoholism; Synergy/On medications/medication
Disease Mechanism & Classification
Class: CLASS/Liver involvement/disorder (ex); CLASS/Liver/gallbladder/ducts (category)
Drugs: DRUG/Reaction to medication/drug induced (ex)
Process: PROCESS/Complicating disorder (ex); PROCESS/Drug induced disorder (ex); PROCESS/Poisoned organ/system (category)
Treatment
Drug Therapy - Contraindication: RX/Isoniazide (INH)
Other Treatments: TX/Avoidance offending agents (indication).
Definition: Be the first to add a definition for Drug induced Hepatitis.
External Links Related to Drug induced Hepatitis.: Google; Wikipedia; Merck; Images; PubMed (National Library of Medicine); NGC (National Guideline Clearinghouse); Medscape (eMedicine); Harrison's Online (accessmedicine); NEJM (The New England Journal of Medicine)

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