Disease Information for Doxorubicin (Adriamycin/Doxil) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Baldness/Alopecia
Bluish/black pigmentation/nails
Hair loss
Non-scarring Alopecia/balding
Dark urine
URINE Color Red
URINE Orange-red colored
Laboratory Tests
Abnormal Lab Findings - Increased
Platelet count (Lab)
Associated Diseases & Rule outs
Rule Outs
Myocarditis, viral
Associated Disease & Complications
Acute Myelogenous/Myeloblastic Leukemia AML
Agranulocytosis
Anemia, aplastic
Bone marrow failure/exhaustion
Cardiomyopathy
Congestive heart failure
Constrictive pericarditis/chronic
Drug induced Baldness/Alopecia
Drug induced Cardiomyopathy/Cardiotoxicity.
Drug induced Hair loss
Drug induced Myelosuppression.
Granulocytopenia/Neutropenia
Hand-foot dermatitis/chemo syndrome
Hyperpigmentation
Mucositis, oral
Myelosuppression
Myocarditis
Myocarditis, acute
Myocarditis, toxic
PPE/Palmar-plantar erythrodysesthesia/ ChemoRX
Stomatitis
Thrombocytopenia
Thrombocytosis
Disease Synergy - Causes
Synergy/Congestive heart failure
Disease Mechanism & Classification
Drugs
DRUG/ABVD ChemoRX protocol (comb)
DRUG/ACE protocol drug combination (ex)
DRUG/Anthracyclines (ex)
DRUG/Anti-tumor antibiotics (example)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/CHOP ChemoRx Protocol (Comb)
DRUG/Cytotoxic/chemotherapy medication (example)
DRUG/H-CAP protocol (four drugs) (comb)
DRUG/M-VAC ChemoRx protocol (comb)
DRUG/Topoisomerase II inhibitor anti-cancer drug
DRUG/Topoisomerase inhibitor anti-cancer drug
DRUG-Liver metabolism/bile excretion
Pathophysiology
Pathophysiology/Myocardium Toxic Effect
Synonyms
Synonym
(8S cis) 10 ((3 Amino 2,3,6 trideoxy alpha L lyxo hexopyranosyl)oxy) 7,8,9,10 tetrahydro 6,8,11 trihydroxy 8 (hydroacetyl) 1 methoxy 5,12 naphthacenedione, (8S cis) 10 ((3 Amino 2,3,6 trideoxy alpha L lyxo hexopyranosyl)oxy) 7,8,9,10 tetrahydro 6,8,11 trihydroxy 8 (hydroxyacetyl) 1 methoxy 5,12 naphthacenedione, 14 Hydroxydaunomycin, 5,12 Naphthacenedione 10 ((3 amino 2,3,6 trideoxy alpha L lyxo hexopyranosyl)oxy) 7,8,9,10 tetrahydro 6,8,11 trihydroxy 8 (hydroxyacetyl) 1 methoxy (8S cis), ADM, ADR, DOX, Doxorubicin, Doxorubicin (product), Doxorubicin (substance), DOXORUBICIN PREPARATION, Doxorubicina, Hydroxyl Daunorubicin, Hydroxyldaunorubicin, Brand name/Adriamycin (Doxorubicin), Brand name/Doxil (Doxorubicin) lipid preparation, Brand name/Rubex (Doxorubicin), Britain-BNF/Caelyx (Doxorubicin), Britain-BNF/Myocet (Doxorubicin)
Treatment
Drug Therapy - Indication
RX/Dexrazoxane (Zenecard)
RX/N-Acetylcysteine (NAC) IV ?
Definition

Cancer chemotherapy drug; antibiotic class

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External Links Related to Doxorubicin (Adriamycin/Doxil) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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