Disease Information for Dofetilide (Tikosyn) Administration/Toxicity

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Associated Diseases & Rule outs
Associated Disease & Complications
Cardiac arrhythmias
Drug induced Arrhythmias
Torsades de pointes/ventricular tachycardia
Disease Mechanism & Classification
Drugs
DRUG/Anti-arrhythmic medication (example)
DRUG/Cardiology usage
DRUG/Cardiovascular meds (examples)
DRUG/Class III antiarrhythmic agent (example)
DRUG/Potassium channel block myocardium
DRUG/Proarrhythmic drug effect (example)
DRUG/Specialized usage (example)
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
Dofetilide (Tikosyn) administration, Brand name/Tikosyn (Dofetilide)
Treatment
Drug Dosage
DRUG/2000 New drug (RX)
DRUG/Dose 0.125 mgms (Unit/Pill/Capsule size)
DRUG/Dose 0.25 mgms (Unit/Pill/Capsule size)
DRUG/Dose 0.5 mgm (Unit/Pill/Capsule size)
DRUG/Dose BID Medication
DRUG/Dose Extended time release/XT/SA (example)
DRUG/Injectable medication (parenteral)
DRUG/Oral medication (ex)
DRUG/Orally ineffective drug
-Renal excretion important pathway/drug
Definition

Anti-arrhythmic medication; Von Williams class III with more atrial fibrillation conversion use; Pro-arrhythmic

torsade de pointes with prolonged QT interval; Very sensitive to dose problems with renal failure

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External Links Related to Dofetilide (Tikosyn) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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