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Disease Information for Dofetilide (Tikosyn) Administration/Toxicity

Associated Diseases & Rule outs

Associated Disease & Complications

Cardiac arrhythmias

Drug induced Arrhythmias

Torsades de pointes/ventricular tachycardia

Disease Mechanism & Classification

Drugs

DRUG/Anti-arrhythmic medication (example)

DRUG/Cardiology usage

DRUG/Cardiovascular meds (examples)

DRUG/Class III antiarrhythmic agent (example)

DRUG/Potassium channel block myocardium

DRUG/Proarrhythmic drug effect (example)

DRUG/Specialized usage (example)

Process

PROCESS/Medication/Drug (CONFIRM dose/before treatment)

Synonyms

Synonym

Dofetilide (Tikosyn) administration, Brand name/Tikosyn (Dofetilide)

Treatment

Drug Dosage

DRUG/2000 New drug (RX)

DRUG/Dose 0.125 mgms (Unit/Pill/Capsule size)

DRUG/Dose 0.25 mgms (Unit/Pill/Capsule size)

DRUG/Dose 0.5 mgm (Unit/Pill/Capsule size)

DRUG/Dose BID Medication

DRUG/Dose Extended time release/XT/SA (example)

DRUG/Injectable medication (parenteral)

DRUG/Oral medication (ex)

DRUG/Orally ineffective drug

-Renal excretion important pathway/drug

Definition

Anti-arrhythmic medication; Von Williams class III with more atrial fibrillation conversion use; Pro-arrhythmic

torsade de pointes with prolonged QT interval; Very sensitive to dose problems with renal failure

(Edit)

External Links Related to Dofetilide (Tikosyn) Administration/Toxicity

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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