- Differential Diagnosis
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- Disease Information
- Disease Comparison
-
Disease Processes ▼
- Auto Immune
- Vascular-Arteriosclerosis
- Biochemical
- Congenital-developmental
- Deficiency
- Degenrative-Necrosis
- Electromagnetic-Physics
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Major Organs-Systems ▼
- Systemic
- Pediatric
- Nervous & Sensory System (Neurology)
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- Endocrine System
- Immune System
- Musculoskeletal System
- Genital Reproductive System
- Hematopoietic System (Hematology)
- Lymphatic System
- Tissue/Cells/Organelles
Disease Information for Disulfiram (Antabuse) Administration/Toxicity
- Clinical Manifestations
- Signs & Symptoms
- Plethora/Red face/Ruddy look
- Brief Blood pressure increase/sign:
- Dizzy on Standing/Giddy Response
- High blood pressure/sign
- Orthostatic drop in blood pressure
- Red/erythema skin discoloration
- Tachycardia/Fast heart rate
- Alcohol induced Flushing
- Cold clammy skin
- Erythroderma
- Facial erythema
- Facial flushing/Beet red
- Flushing
- Flushing/upper body
- Yellow skin discoloration
- Impotence, relative
- Nausea
- Vomiting
- Apathy/Indifference
- Clumsiness/poor coordination
- Confusion/Disoriented
- Delirium
- Delirium/Agitated delirium
- Fine-motor coordination problems
- Lethargy/torpor
- Motor and sensory neuropathy/Polyneuropathy signs
- Paresthesias
- Poor coordination legs/feet
- Seizures
- Stupor/poor reponse to stimulus
- Manic behavior
- Bone Pain Triggered by Alcohol
- Bone Pains
- Certain drugs trigger rash/flushing/itch
- Cold clammy pale status
- Collapse/Prostration
- Listlessness/lassitude
- Laboratory Tests
- Abnormal Lab Findings - Decreased
- Norepinephrine, plasma (Lab)
- Associated Diseases & Rule outs
- Rule Outs
- Guillain-Barre syndrome
- Associated Disease & Complications
- Convulsions (grand mal)
- Disufiram (Antabuse) effect/toxicity
- Disulfiram-like drug reaction/alcohol
- Drug induced Impotence.
- Drug induced Peripheral neuropathy.
- Fetal anomaly
- Hypertension
- Impotence/Erectile dysfunction disorder
- Orthostatic syncope Hypotension
- Peripheral neuropathy
- Polyneuritis
- Psychosis
- Sedation/torpor induced
- Toxic hepatitis
- Toxic peripheral/polyneuropathy
- Polyneuropathy
- Disease Mechanism & Classification
- Drugs
- DRUG/Anti-addiction medication (example)
- DRUG/Inhibits acetaldehyde catabolism/oxidation
- DRUG/Inhibits Dopamine betahydroxylase/Norepinephrine production
- DRUG/Specialized usage (example)
- DRUG/Teratogenic potential/effect (D plus )
- DRUG/Lowers seizure threshold
- Pathophysiology
- Pathophysiology/CNS depression
- Process
- PROCESS/Medication/Drug (CONFIRM dose/before treatment)
- Toxin
- TOXIN/Causes Flushing/Redness
- TOXIN/Latency after exposure/ingestion
- TOXIN/Lethal possible
- TOXIN/Slow curve fast break 24 hrs
- Synonyms
- Synonym
- Antabus effect, Antabuse effect, Brand name/Antabuse (Disulfiram)
- Treatment
- Drug Therapy - Contraindication
- RX/Ethanol (Eythyl alcohol) infusion
- RX/Warfarin (Coumadin)
- Drug Dosage
- DRUG/.1990 or before
- DRUG/Dose 250 mgm (Unit/Pill/Capsule size)
- DRUG/Dose 500 mgm (Unit/Pill/Capsule size)
- DRUG/Dose once daily (RX)
- DRUG/Generic available
- DRUG/Oral medication (ex)
- Definition
-
Specialized drug; alcohol addiction drug; inhibits alcohol
metabolism build up acetaldehyde levels highly symptomatic; oral preparation
(Edit)
- External Links Related to Disulfiram (Antabuse) Administration/Toxicity
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)
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