Disease Information for Paroxysmal Nocturnal Hemoglobinuria: Disease Mechanism & Classification

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Class
CLASS/Primary organ/system disorder (ex)
CLASS/Erythrocyte disorder (ex)
CLASS/Hematologic (category)
CLASS/Stem cell disease (ex)
Pathophysiology
Pathophysiology/Chromosome gene/segment deletion (ex)
Pathophysiology/Gene locus Chromosome X.
Pathophysiology/Gene Locus Identified/OMIM database
Pathophysiology/Gene locus PIG-A gene /X-chromosome
Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
Pathophysiology/Arterial Occlusion
Pathophysiology/Thrombosis veins lower ext/iliac/femoral
Pathohysiology/PIGA defect/GPI Membrane Anchor fails
Pathophysiology/Chronic Iron loss
Pathophysiology/Complement sensitivity
Pathophysiology/Erythrocyte membrane disorder
Pathophysiology/Hemolysis
Pathophysiology/Hemolytic process/effect
Pathophysiology/Intrinsic CO production increased
Pathophysiology/Myelodysplasia process
Pathophysiology/Non-immune hemolytic anemia
Pathophysiology/Plasma c3b inactivatior/failure
Pathophysiology/RBC membrane defect/complement risk
Pathophysiology/RBC membrane glycosyl-phosphatidyl-inositol path
Pathophysiology/RBC membrane/Missing key proteins
Pathophysiology/Stem cell defect
Pathophysiology/Unusual sensitive RBC to C3 in plasma
Pathophysiology/Complement activation
Pathophysiology/Granulocyte lyses/manifestation
Process
PROCESS/Allergy/collagen/autoimmune (category)
PROCESS/Episodic disorder (ex)
PROCESS/Hereditofamilial (category)
PROCESS/Idiopathic/unclassified/unknown (category)
PROCESS/INCIDENCE/Acquired disorder
PROCESS/INCIDENCE/Rare disease (ex)
PROCESS/Pre-Leukemic condition (ex)
PROCESS/Reference organ/system (category)
PROCESS/Coagulation derangement/disorder (ex)
PROCESS/Somatic mutation/not hereditary
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