Disease Information for Dimercaprol (BAL) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Nausea
Vomiting
Drooling
Excess salivation/hypersalivation
Foaming/Frothing at the mouth
Sialorrhea/Ptyalism
Muscle Pain
Myalgias
Apathy/Indifference
Dysesthesias
Headache
Headache, frontal
Lethargy/torpor
Paresthesias
Seizures
Coryza
Runny nose/rhinorrhea
Dysuria
Fever
Fever Febrile Possible
Flu-Like Syndrome
High body temperature
Listlessness/lassitude
Lacrimation/excess tearing
Tearing
Demographics & Risk Factors
Established Disease Population
Patient/G6PD RBC hemolysis
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Acute inflammatory markers elevated (Lab)
Diagnostic Test Results
Isotope Scan
Isotope/Thyroid Scan Abnormal
Associated Diseases & Rule outs
Associated Disease & Complications
Acute Renal Failure
Azotemia/Acute
Convulsions (grand mal)
Dimercaprol (BAL) effect/toxicity
Drug induced Renal failure,
Glucose-6-PD Hemolytic crisis ('triggers')
Toxic nephritis/Chronic persistent
Toxic Nephritis/Nephropathy
Urticaria/hives
Disease Mechanism & Classification
Drugs
DRUG/Antidote/specific medication (example)
DRUG/Chelating agent (example)
DRUG/Teratogenic potential/effect (D plus )
DRUG/Lowers seizure threshold
Pathophysiology
Pathophysiology/CNS depression
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
1 Propanol 2,3 dimercapto, 1,2 Dithioglycerol, 2,3 Dimercapto 1 propanol, 2,3 Dimercaptopropanol, 2,3 Dithiopropan 1 o1, Anti Lewisite Agent British, Anti Lewisite British, BAL, BAL British Anti Lewisite, BAL Dimercaprol, British anti lewisite, British Anti Lewisite Agent, Dimercaprol, Dimercaprol (product), Dimercaprol (substance), DIMERCAPROL PREPARATION, Dimercaptopropanol, Dithioglycerol, Brand name/BAL (Dimercaprol), Synonym/British anti-Lewisite administration
Treatment
Drug Therapy - Contraindication
RX/Penicillamine (Cupramine)
Drug Dosage
DRUG/.$$$$ Very Expensive
DRUG/.$$$$$ Most Expensive
DRUG/.1990 or before
DRUG/Dose 100 mgm/ml vial
DRUG/Dose Multi-dose Vial preparation
DRUG/Dose NOT Intravenous
DRUG/Injectable medication (parenteral)
DRUG/Intramuscular injection RX
Definition

Chelating drug used for arsenic and other heavy metals; parenteral preparation; may precitate renal toxicity; BAL is named for British Anti-Lewisite (arsine gas in WW I)

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External Links Related to Dimercaprol (BAL) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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