Disease Information for Diltiazem (Cardizem) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Hypotension with Relative Bradycardia
Low Blood Pressure
Flushing
Rash
Diagnostic Test Results
EKG (ECG)
EKG/Widened QRS pattern (ECG)
EKG/AV Nodal Block/Complete
EKG/Sinus bradycardia (ECG)
EKG/Changes/abnormalities (ECG)
Associated Diseases & Rule outs
Rule Outs
Digitalis toxicity/poisoning
Associated Disease & Complications
Bradyarrhythmias
Cardiac conduction defects
Congestive heart failure
Drug induced Photosensitivity rash
Drug rash/Drug induced rash
Heart block, complete
Hypotension
Photosensitivity dermatitis
Phototoxicity
Pulmonary edema
Sinus bradycardia
Disease Synergy - Causes
Synergy/Congestive heart failure
Disease Mechanism & Classification
Drugs
DRUG/Anti-anginal medication (example)
DRUG/Anti-arrhythmic medication (example)
DRUG/Antihypertensive medication (examples)
DRUG/Calcium-channel blocker meds (examples)
DRUG/Cardiovascular meds (examples)
DRUG/Class IV antiarrhythmic agent (example)
DRUG/Cytochrome p450 CYP3A Pathway
DRUG/Cytochrome p450 degradation/pharmacology (ex)
DRUG/Important Acute care drugs (example)
DRUG/Non-dihydropyridine calcium channel blocker (ex)
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin
TOXIN/Decreases Blood Pressure
TOXIN/Decreases Heart Rate
TOXIN/Hypotension relative bradycardia
TOXIN/Inotropic decrease/shock (ex)
Synonyms
Synonym
1,5 Benzothiazepin 4(5H) one 3 (acetyloxy) 5 (2 (dimethylamino)ethyl) 2,3 dihydro 2 (4 methoxyphenyl) (2S cis), diltiazem, Diltiazem (product), Diltiazem (substance), DILTIAZEM PREPARATION, Brand name/Cardizem (Diltiazem), Brand name/Cartia SR (Diltiazem), Brand name/Dilacor (Diltiazem), Brand name/Diltia XT (Diltiazem), Brand name/Teczem (Enalapril-Diltiazem), Brand name/Tiamate (Diltiazem), Brand name/Tiazac (Diltiazem), Brand name/Vasocardol (Diltiazem)
Treatment
Drug Therapy - Indication
RX/Calcium chloride injection/infusion
RX/Calcium gluconate infusion
RX/Glucagon
Drug Dosage
DRUG/Dose 180 mgms (Unit/Pill/Capsule size)
DRUG/Dose 240 mgms (Unit/Pill/Capsule size)
DRUG/Dose 60 mgm (Unit/Pill/Capsule size)
DRUG/Dose Extended time release/XT/SA (example)
DRUG/Dose Infusion mix 125 mgm/125 ml (CONFIRM this)
DRUG/Dose may repeat
DRUG/Infusion option medication
DRUG/Injectable medication (parenteral)
DRUG/Intravenous administraton RX
DRUG/IV requires lesser dose/Caution
DRUG/Oral medication (ex)
Definition

Calcium channel blocker medication; Cardiovascular drugs with selective and varied anti-vasospasm, hypertension, angina, and anti-arrhythmia activity; Diltiazem is used for atrial arrhythmia control; Oral and parenteral drug

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External Links Related to Diltiazem (Cardizem) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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