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- Disease Information
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Disease Processes ▼
- Auto Immune
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Major Organs-Systems ▼
- Systemic
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Disease Information for Diabetes mellitus/juvenile (Type I)
- Clinical Manifestations
- Signs & Symptoms
- Pruritis Itching
- Accelerated growth Child
- Anorexia in Infant
- Diarrhea
- Excessive thirst/polydipsia
- Failure to Thrive
- Failure to Thrive Child
- Failure to thrive/infant sign
- Feeding/Apetite Problems Child
- Nausea
- Polyphagia
- Vomiting
- Salivary Gland Enlargement
- Cramping in Extremities
- Muscle cramps/spasms
- Weak/Weak as a kitten (symptom)
- Headache
- Paresthesias
- Spasms in Both Legs
- Tall child
- Diuresis/Large urine volumes
- Polyuria
- Polyuria and polydipsia
- Chronic Fatigue
- Enervated/extreme acute fatigue
- School/job performance decline
- Short stature
- Short stature Child
- Thirst Increased
- Weakness
- Weakness non-neuromuscular/systemic
- Weight Loss
- Visual acuity decreasing
- Visual symptoms
- Disease Progression
- Course/Chronic disorder
- Course/Chronic only
- Demographics & Risk Factors
- Established Disease Population
- Patient/Autoimmune disorder
- Patient/Sepsis
- Patient/Type I/diabetic (juvenile)
- Population Group
- Child
- Population/Pediatrics population
- Family History
- Family history/Diabetes mellitus
- Sex & Age Groups
- Population/Child
- Population/Children/all
- Population/Old child
- Laboratory Tests
- Abnormal Lab Findings (Non Measured)
- DNATest specific/genetics laboratory/abnormality (Lab)
- Serum lipids increased (Lab)
- HLA B27 (Lab)
- Abnormal Lab Findings - Decreased
- Insulin C-Peptide type, serum (Lab)
- Insulin level (Lab)
- Abnormal Lab Findings - Increased
- Anti-GAD antibodies
- Anti-Glutamic Acid decarboxylase antibodies/GAD
- Anti-insulin antibodies
- Anti-parietal cell antibody (Lab)
- Anti-Pancreatic islet cell (512) antibodies
- Anti-Islet cell Antibodies
- Glucose, blood (Lab)
- Glutamic Acid Dehydrogenase Antibodies/Anti-GAD (Lab)
- Postprandial Glucose
- URINE Glucose
- Diagnostic Test Results
- Other Tests & Procedures
- TEST/Glucose intolerance/GTT abnormal
- X-RAY
- Xray/Delayed bone age/slow epiphysis closures
- Associated Diseases & Rule outs
- Associated Disease & Complications
- Diabetic autonomic neuropathy syndrome
- Diabetic ketoacidosis/coma
- Hyperglycemia
- Hyperlipidemia
- Retinopathy
- Skin infections
- Diabetes mellitus/juvenile (Type I)
- Disease Synergy - Causes
- Synergy/Carbohydrate excess/diet
- Disease Mechanism & Classification
- Class
- CLASS/Pediatric disorders (ex)
- CLASS/Pancreas/accessory (category)
- Pathophysiology
- Pathophysiology/Cytokine gene polymorphism
- Pathophysiology/Gene locus 12q24.2
- Pathophysiology/Gene locus 1p13
- Pathophysiology/Gene locus 6p21.3
- Pathophysiology/Gene locus Chromosome 1
- Pathophysiology/Gene locus chromosome 12
- Pathophysiology/Gene locus Chromosome 6
- Pathophysiology/Gene locus Chromosome X.
- Pathophysiology/Gene Locus Identified/OMIM database
- Pathophysiology/Gene locus Xp11.23-q13.3
- Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
- Pathophysiology/Hyperglycemia/reactive/AM/Smolgi
- Pathophysiology/Islets of Langerhans involvement
- Process
- PROCESS/Autoimmune disorder (ex)
- PROCESS/Endocrine/humoral disorders (category)
- PROCESS/Metabolic/storage disorder (category)
- PROCESS/Systemic illness (ex)
- Synonyms
- Synonym
- Diab mell +comp juvenile, Diabetes mellitus juvenile type + unspecified complication, Diabetes mellitus juvenile type with unspecified complication, Diabetes mellitus juvenile type with unspecified complication (disorder), Insulin dependent diabetes mellitus with unspecified complications, Type 1 diabetes mellitus with unspecified complication, Type I diabetes mellitus with complication, Type I diabetes mellitus with complication (disorder), Type I diabetes mellitus with unspecified complication, Synonym/LADA (Late autoimmune Diabetes adult) variant
- Treatment
- Drug Therapy - Indication
- RX/Insulin
- Other Treatments
- TX/Diet restriction treatment.
- TX/Potential Stem Cell Research RX
- Definition
-
Autoimmune/post-infectious/genetic cause of islet beta cell wipeout causing zero output of insulin; treatment requires constant low dose insulin else brittle effect; juvenile onset and different phyasiology from type II DM where insulin levels are high not absent but insulin resistance obtains; acidosis is reguar event with type I rare in type II but much overlap; oral drugs not really effective
(Edit)
- External Links Related to Diabetes mellitus/juvenile (Type I)
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)