Disease Information for Wilms tumor: Definition

  • A kidney cancer that occurs in children usually younger than 5 years.

    Wilms' Tumor; Embryoma Kidney; Embryonal Adenomyosarcoma Kidney; Embryonal Carcinosarcoma Kidney; Embryonal Mixed Tumor Kidney; Nephroblastoma;

    Wilms' Tumor is the most common form of kidney cancer in children, accounting for six to eight percent of all childhood cancers; The exact cause is not known, although it is thought to be inherited in some cases; An abdominal swelling is the most common symptom usually leading to early detection of the disease; Wilms' Tumor can often be treated successfully depending on the stage of the tumor at detection and the age and general health of the child

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    Birch-Hirschfeld syndrome; Birch-Hirschfeld tumour; Wilms nephroblastoma; Wilms' syndrome; Adenomyosarcoma, embryoma of the kidney, embryonal adenosarcoma, embryonal carcinosarcoma, embryonal mixed tumor, embryonal nephroma, embryonal sarcoma nephroblastoma;

    Wilms' tumour is a highly malignant, usually unilateral and rapidly developing tumour of the kidney, composed of malignant epithelial and mesodermal cells; Initially, asymptomatic; later, moderate local pain, nausea, vomiting, apathy, and fever; There is also pallor, weight loss, abdominal distension, and blood hypertension; It is the most common malignous kidney tumour in children, usually affecting children aged 3-4 years; 75 percent of patients are under 5 years, but it has also been reported in adults; In the past, the mortality from this cancer was extremely high; Newer approaches to therapy have been very effective in controlling the tumor; In a small proportion of patients Wilms" tumor occurs in conjunction with absence of the iris and the familial form of the association is inherited as an autosomal dominant trait