Disease Information for Meningitis, tuberculosis: Definition

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  • A form of bacterial meningitis caused by MYCOBACTERIUM TUBERCULOSIS or rarely MYCOBACTERIUM BOVIS; The organism seeds the meninges and forms microtuberculomas which subsequently rupture; The clinical course tends to be subacute, with progressions occurring over a period of several days or longer; Headache and meningeal irritation may be followed by SEIZURES, cranial neuropathies, focal neurologic deficits, somnolence, and eventually COMA; The illness may occur in immunocompetent individuals or as an OPPORTUNISTIC INFECTION in the ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunodeficiency syndromes-------(From Adams et al, Principles of Neurology, 6th ed, pp717-9)---------

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