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Disease Information for Felty's syndrome: Definition
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- 168 possible findings found
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- External Links Related to Felty's syndrome
A combination of rheumatoid arthritis, splenomegaly, leukopenia, pigmented spots on lower extremities, and other evidence of hypersplenism (anemia and thrombocytopenia); (From Dorland, 27th ed); Rheumatoid factor is strongly positive; neutropenia responds to splenectomy;-------------------------------------
Also known as:
Arthritis-splenomegaly-leukopenia syndrome, hypersplenism; neutropenic hypersplenism-arthritis syndrome; primary splenic neutropenia with arthritis, rheumatoid arthritis-splenomegaly, rheumatoid arthritis-hypersplenism, rheumatoid arthritis-splenomegaly-leukopenia syndrome.
Anatole Marie Émile Chauffard
Augustus Roi Felty
Sir George Frederick Still
Atypical form of rheumatoid arthritis with fever, splenomegaly and leukopenia and, in some cases, anaemia and thrombocytopenia. Other features can include anorexia, weight loss, recurrent infections, brown pigmentation of exposed skin surfaces, peripheral neuropathy, carpal tunnel syndrome, arteritis, general malaise, pain in the upper left quadrant of the abdomen, Raynaud"s syndrome and scleritis. Occurs most often in patients with a sustained period of illness, more often in women than in men.
Still disease or syndrome, also called Still-Chauffard-Felty syndrome, is a juvenile form. See under Sir George Frederick Still, English paediatrician, 1868-1941.
Splenomegaly with Rheumatoid Arthritis
Felty Syndrome is a rare form of Rheumatoid Arthritis, a disorder characterized by painful, stiff, and swollen joints. Major symptoms and physical findings of Felty Syndrome include an unusually large spleen (splenomegaly) and abnormally low levels of certain white blood cells (neutophils [neutropenia]). As a result of neutropenia, affected individuals may have an increased susceptibility to certain infections. Other symptoms associated with Felty Syndrome may include fatigue, fever, weight loss, and/or discoloration of patches of skin (brown pigmentation). The exact cause of Felty Syndrome is unknown. It is believed to be an autoimmune disorder.