Disease Information for Crohn's colitis/large bowel: Definition

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  • Crohns disease primarily in colon;this is a chronic transmural inflammation of terminal ileum and colon and entire gut, potentially; Extra-colonic manifestations are often associated and involve the liver, eyes, joints and skin;

    Genetic links, ethnic predisposion and responses to certain therapies suggest auto-immune disorder; No offending antigen ever found

    (Edit)

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